Cutaneous Appendageal Carcinoma Incidence and Survival Patterns in the United States: A Population-Based Study

OBJECTIVE To examine incidence patterns of patients diagnosed as having cutaneous appendageal carcinoma (CAC). DESIGN Population-based study using the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute data from 1978 through 2005. PARTICIPANTS A total of 1801 subjects from SEER 16 registries (2001-2005) for incidence analyses, 2228 from SEER 9 registries (1987-2005) for trend analysis, and 1984 subjects (1992-2004) for survival analysis. MAIN OUTCOME MEASURE Incidence rates (IRs) per 1 million person-years according to anatomic site, race, sex, age, and histologic type. RESULTS Cutaneous appendageal carcinomas are uncommon (age-adjusted IR, 5.1 per 1 million person-years), with the IR among men statistically significantly higher than women (6.3 vs 4.2, respectively; male to female IR ratio 1.51; P