Three cases of Dowling Degos disease in two families

Dowling Degos disease is a rare condition inherited as autosomal dominant trait characterized by numerous, asymptomatic, symmetrical, progressive, small, round-pigmented macules over axillae and groins, face, neck, arms and trunk, scattered comedo-like lesions (dark dot follicles) and pitted acneifo...

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Veröffentlicht in:Indian journal of dermatology, venereology, and leprology venereology, and leprology, 2009-07, Vol.75 (4), p.398-400
Hauptverfasser: Bhagwat, PV, Tophakhane, RS, Shashikumar, BM, Noronha, Tonita M, Naidu, Varna
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container_issue 4
container_start_page 398
container_title Indian journal of dermatology, venereology, and leprology
container_volume 75
creator Bhagwat, PV
Tophakhane, RS
Shashikumar, BM
Noronha, Tonita M
Naidu, Varna
description Dowling Degos disease is a rare condition inherited as autosomal dominant trait characterized by numerous, asymptomatic, symmetrical, progressive, small, round-pigmented macules over axillae and groins, face, neck, arms and trunk, scattered comedo-like lesions (dark dot follicles) and pitted acneiform scars. Histopathology is diagnostic. We are hereby reporting three cases of Dowling Degos disease belonging to two families. Our first and second case belonged to the same family, whereas our third case belonged to different family. In our series, all the patients had onset after puberty. All three cases had reticulate pigmentation over face and/or flexures, black comedones and follicular pits. On histopathological examination of the skin biopsy taken from the lesion over the back, all these patients showed classical histopathological features of Dowling Degos disease. We feel that one should investigate the patient presenting with reticulate pigmentation over the face and flexures with blackish comedone-like lesions, because histopathological features of this condition are unmistakable.
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We feel that one should investigate the patient presenting with reticulate pigmentation over the face and flexures with blackish comedone-like lesions, because histopathological features of this condition are unmistakable.</description><identifier>ISSN: 0378-6323</identifier><identifier>EISSN: 0973-3922</identifier><identifier>EISSN: 1998-3611</identifier><identifier>DOI: 10.4103/0378-6323.53139</identifier><identifier>PMID: 19584468</identifier><identifier>CODEN: IJDLDY</identifier><language>eng</language><publisher>New Delhi: Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Care and treatment ; Complications and side effects ; Dermatology ; Development and progression ; Diagnosis ; Dowling Degos disease, Reticulate pigmentation, Pigmented comedones ; Female ; Females ; Hair and nails disorders ; Humans ; Keratosis ; Male ; Medical diagnosis ; Medical sciences ; Middle Aged ; Patients ; Pedigree ; Physical examinations ; Pigmentary diseases of the skin ; Pigmentation disorders ; Pigmentation Disorders - diagnosis ; Pigmentation Disorders - drug therapy ; Pigmentation Disorders - genetics ; Retinoids - administration &amp; dosage ; Risk factors ; Skin Diseases, Genetic - diagnosis ; Skin Diseases, Genetic - drug therapy ; Skin Diseases, Genetic - genetics</subject><ispartof>Indian journal of dermatology, venereology, and leprology, 2009-07, Vol.75 (4), p.398-400</ispartof><rights>Copyright 2009 Indian Journal of Dermatology, Venereology and Leprology.</rights><rights>2009 INIST-CNRS</rights><rights>COPYRIGHT 2009 Medknow Publications and Media Pvt. 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We feel that one should investigate the patient presenting with reticulate pigmentation over the face and flexures with blackish comedone-like lesions, because histopathological features of this condition are unmistakable.</abstract><cop>New Delhi</cop><pub>Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)</pub><pmid>19584468</pmid><doi>10.4103/0378-6323.53139</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Aged
Biological and medical sciences
Care and treatment
Complications and side effects
Dermatology
Development and progression
Diagnosis
Dowling Degos disease, Reticulate pigmentation, Pigmented comedones
Female
Females
Hair and nails disorders
Humans
Keratosis
Male
Medical diagnosis
Medical sciences
Middle Aged
Patients
Pedigree
Physical examinations
Pigmentary diseases of the skin
Pigmentation disorders
Pigmentation Disorders - diagnosis
Pigmentation Disorders - drug therapy
Pigmentation Disorders - genetics
Retinoids - administration & dosage
Risk factors
Skin Diseases, Genetic - diagnosis
Skin Diseases, Genetic - drug therapy
Skin Diseases, Genetic - genetics
title Three cases of Dowling Degos disease in two families
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