Absence of linkage between the interleukin-6 gene (−174 G/C) polymorphism and migraine

To assess the role of interleukin-6 (IL-6) in migraine, we analyzed the −174 G/C IL-6 gene polymorphism in 268 patients with migraine and 305 controls. No significant difference in the distribution of IL-6 genotypes ( χ 2=0.601, P=0.74) and allelic frequencies ( χ 2=0.024, P=0.876) was found. When p...

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Veröffentlicht in:	Neuroscience letters 2003-06, Vol.343 (3), p.155-158
Hauptverfasser:	Rainero, Innocenzo, Salani, Giuliana, Valfrè, Walter, Savi, Lidia, Rivoiro, Chiara, Ferrero, Margherita, Pinessi, Lorenzo, Grimaldi, Luigi M.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Anxiety Aura Biological and medical sciences Cohort Studies DNA - genetics Female Genetic Linkage Genotype Humans Interleukin-6 Interleukin-6 - genetics Male Medical sciences Middle Aged Migraine Migraine Disorders - genetics Migraine with Aura - genetics Migraine without Aura - genetics Neurology Polymorphism, Genetic - genetics Reverse Transcriptase Polymerase Chain Reaction Tension-type headache Vascular diseases and vascular malformations of the nervous system
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