Curcumin Nanoparticles Improve the Physicochemical Properties of Curcumin and Effectively Enhance Its Antioxidant and Antihepatoma Activities

Curcumin (CUR), a natural polyphenol isolated from tumeric (Curcuma longa), has been documented to possess antioxidant and anticancer activities. Unfortunately, the compound has poor aqueous solubility, which results in poor bioavailability following high doses by oral administration. To improve the...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2010-06, Vol.58 (12), p.7376-7382
Hauptverfasser:	Yen, Feng-Lin, Wu, Tzu-Hui, Tzeng, Cheng-Wei, Lin, Liang-Tzung, Lin, Chun-Ching
Format:	Artikel
Sprache:	eng
Schlagworte:	anticarcinogenic activity Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology antioxidant activity Antioxidants - chemistry Antioxidants - pharmacology Biological Availability Carcinoma, Hepatocellular - drug therapy Cell Line, Tumor cell lines Chemical Phenomena Curcuma longa curcumin Curcumin - chemistry Curcumin - pharmacology cytotoxicity Drug Compounding - methods Food Chemistry/Biochemistry hepatoma human diseases human nutrition Humans lipid peroxidation Nanoparticles - chemistry nanotechnology Particle Size particles physicochemical properties phytochemicals polyphenols Solubility
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