Imaging of persistent cAMP signaling by internalized G protein-coupled receptors

G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors. They mediate the effects of several endogenous cues and serve as important pharmacological targets. Although many biochemical events involved in GPCR signaling have been characterized in great detail, little is...

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Veröffentlicht in:	Journal of molecular endocrinology 2010-07, Vol.45 (1), p.1-8
Hauptverfasser:	Calebiro, Davide, Nikolaev, Viacheslav O, Lohse, Martin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cyclic AMP - metabolism Endocytosis - physiology Endosomes - metabolism Endosomes - ultrastructure Fluorescence Resonance Energy Transfer - instrumentation Fluorescence Resonance Energy Transfer - methods Luminescent Proteins - metabolism Receptors, G-Protein-Coupled - metabolism Review Second Messenger Systems - physiology Thyroid Gland - cytology Thyroid Gland - metabolism
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