Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya
Pregnant women with Hepatitis B virus HBV represent a major reservoir of the virus in the community. Data regarding the prevalence of HBV in pregnant women and maternal transmission of the virus in Libya are lacking. Hepatitis blood samples from 1,500 pregnant women and 1,500 cord blood samples of t...
Gespeichert in:
| Veröffentlicht in: | Journal of infection in developing countries 2010-03, Vol.4 (3), p.168-170 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 170 |
|---|---|
| container_issue | 3 |
| container_start_page | 168 |
| container_title | Journal of infection in developing countries |
| container_volume | 4 |
| creator | El-Magrahe, Hamida Furarah, Abdul Rahaman El-Figih, Kheiria El-Urshfany, Sued Ghenghesh, Khalifa Sifaw |
| description | Pregnant women with Hepatitis B virus HBV represent a major reservoir of the virus in the community. Data regarding the prevalence of HBV in pregnant women and maternal transmission of the virus in Libya are lacking.
Hepatitis blood samples from 1,500 pregnant women and 1,500 cord blood samples of their neonates delivered at Tripoli Medical Center, Tripoli, were tested for HBsAg by ELISA technique. HBsAg-positive samples were also tested for HBeAg.
HBsAg was detected in 1.5% (23/1,500) pregnant women and in 0.9% (14/1,500) neonates. Although HBsAg was detected at higher rate in pregnant women aged > 25 years [1.8% (22/1,235)] than in pregnant women aged < 25 years [0.4% (1/265)], the difference was not statistically significant (P > 0.05). All HBsAg-positive neonates were born to HBsAg-positive mothers with a rate of maternal transmission at 60.9% (14/23). HBeAg was detected in 21.7% (5/23) and in 7.1% (1/14) of HBsAg-positive pregnant women and neonates, respectively.
Because of the high risk of developing chronic HBV infection at birth among infants born to HBsAg-positive mothers, administration of HBIG in combination with hepatitis B vaccine as post-exposure prophylaxis for such infants is of paramount importance. In addition, universal HBsAg screening of all pregnant women will greatly assist in reducing the maternal transmission of HBV in the country. |
| doi_str_mv | 10.3855/jidc.609 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733342497</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733342497</sourcerecordid><originalsourceid>FETCH-LOGICAL-c310t-ac85e5fbc1090ea6d11154abea9732a2eb15c2b6c6deea96e56dbf3afaf934a3</originalsourceid><addsrcrecordid>eNpdkEtLw0AUhQdRbK2Cv0AGXFjB1Hlk8li2Ra1QcdOthJvJTZmSJnEmEfrvndIq4urce_g4cA4h15xNZKLU48YUehKx9IQMeRqLQEQJO_1zD8iFcxvGVCoVPycDwbyGKhmSjzfo0NZQUagLWmNTQ-cfh7ZpLX5BhbVG2pR0gS10pjOOzqjrbQnehroza6zpeDFz0_U9NTVdWdM2lXmgS5Pv4JKclVA5vDrqiKyen1bzRbB8f3mdT5eBlpx1AehEoSpzzVnKEKKCc65CyBHSWAoQmHOlRR7pqEDvRaiiIi8llFCmMgQ5IneH2NY2nz26Ltsap7GqwBfqXRZLKUMR-rARuf1Hbpp-X99lQkVMpEzF3FPjA6Vt45zFMmut2YLdZZxl-8Gz_eCZH9yjN8fAPt9i8Qv-LCy_AZb5e6c</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2560290571</pqid></control><display><type>article</type><title>Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>El-Magrahe, Hamida ; Furarah, Abdul Rahaman ; El-Figih, Kheiria ; El-Urshfany, Sued ; Ghenghesh, Khalifa Sifaw</creator><creatorcontrib>El-Magrahe, Hamida ; Furarah, Abdul Rahaman ; El-Figih, Kheiria ; El-Urshfany, Sued ; Ghenghesh, Khalifa Sifaw</creatorcontrib><description>Pregnant women with Hepatitis B virus HBV represent a major reservoir of the virus in the community. Data regarding the prevalence of HBV in pregnant women and maternal transmission of the virus in Libya are lacking.
Hepatitis blood samples from 1,500 pregnant women and 1,500 cord blood samples of their neonates delivered at Tripoli Medical Center, Tripoli, were tested for HBsAg by ELISA technique. HBsAg-positive samples were also tested for HBeAg.
HBsAg was detected in 1.5% (23/1,500) pregnant women and in 0.9% (14/1,500) neonates. Although HBsAg was detected at higher rate in pregnant women aged > 25 years [1.8% (22/1,235)] than in pregnant women aged < 25 years [0.4% (1/265)], the difference was not statistically significant (P > 0.05). All HBsAg-positive neonates were born to HBsAg-positive mothers with a rate of maternal transmission at 60.9% (14/23). HBeAg was detected in 21.7% (5/23) and in 7.1% (1/14) of HBsAg-positive pregnant women and neonates, respectively.
Because of the high risk of developing chronic HBV infection at birth among infants born to HBsAg-positive mothers, administration of HBIG in combination with hepatitis B vaccine as post-exposure prophylaxis for such infants is of paramount importance. In addition, universal HBsAg screening of all pregnant women will greatly assist in reducing the maternal transmission of HBV in the country.</description><identifier>ISSN: 1972-2680</identifier><identifier>ISSN: 2036-6590</identifier><identifier>EISSN: 1972-2680</identifier><identifier>DOI: 10.3855/jidc.609</identifier><identifier>PMID: 20351458</identifier><language>eng</language><publisher>Italy: Journal of Infection in Developing Countries</publisher><subject>Adult ; Age Factors ; Female ; Hepatitis B ; Hepatitis B Surface Antigens - immunology ; Hepatitis B virus - immunology ; Hepatitis B, Chronic - epidemiology ; Hepatitis B, Chronic - etiology ; Hepatitis B, Chronic - prevention & control ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical ; Libya - epidemiology ; Post-Exposure Prophylaxis ; Pregnancy ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy Complications, Infectious - etiology ; Pregnancy Complications, Infectious - prevention & control ; Prevalence ; Seroepidemiologic Studies</subject><ispartof>Journal of infection in developing countries, 2010-03, Vol.4 (3), p.168-170</ispartof><rights>2010. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c310t-ac85e5fbc1090ea6d11154abea9732a2eb15c2b6c6deea96e56dbf3afaf934a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20351458$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El-Magrahe, Hamida</creatorcontrib><creatorcontrib>Furarah, Abdul Rahaman</creatorcontrib><creatorcontrib>El-Figih, Kheiria</creatorcontrib><creatorcontrib>El-Urshfany, Sued</creatorcontrib><creatorcontrib>Ghenghesh, Khalifa Sifaw</creatorcontrib><title>Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya</title><title>Journal of infection in developing countries</title><addtitle>J Infect Dev Ctries</addtitle><description>Pregnant women with Hepatitis B virus HBV represent a major reservoir of the virus in the community. Data regarding the prevalence of HBV in pregnant women and maternal transmission of the virus in Libya are lacking.
Hepatitis blood samples from 1,500 pregnant women and 1,500 cord blood samples of their neonates delivered at Tripoli Medical Center, Tripoli, were tested for HBsAg by ELISA technique. HBsAg-positive samples were also tested for HBeAg.
HBsAg was detected in 1.5% (23/1,500) pregnant women and in 0.9% (14/1,500) neonates. Although HBsAg was detected at higher rate in pregnant women aged > 25 years [1.8% (22/1,235)] than in pregnant women aged < 25 years [0.4% (1/265)], the difference was not statistically significant (P > 0.05). All HBsAg-positive neonates were born to HBsAg-positive mothers with a rate of maternal transmission at 60.9% (14/23). HBeAg was detected in 21.7% (5/23) and in 7.1% (1/14) of HBsAg-positive pregnant women and neonates, respectively.
Because of the high risk of developing chronic HBV infection at birth among infants born to HBsAg-positive mothers, administration of HBIG in combination with hepatitis B vaccine as post-exposure prophylaxis for such infants is of paramount importance. In addition, universal HBsAg screening of all pregnant women will greatly assist in reducing the maternal transmission of HBV in the country.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Female</subject><subject>Hepatitis B</subject><subject>Hepatitis B Surface Antigens - immunology</subject><subject>Hepatitis B virus - immunology</subject><subject>Hepatitis B, Chronic - epidemiology</subject><subject>Hepatitis B, Chronic - etiology</subject><subject>Hepatitis B, Chronic - prevention & control</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infectious Disease Transmission, Vertical</subject><subject>Libya - epidemiology</subject><subject>Post-Exposure Prophylaxis</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - epidemiology</subject><subject>Pregnancy Complications, Infectious - etiology</subject><subject>Pregnancy Complications, Infectious - prevention & control</subject><subject>Prevalence</subject><subject>Seroepidemiologic Studies</subject><issn>1972-2680</issn><issn>2036-6590</issn><issn>1972-2680</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkEtLw0AUhQdRbK2Cv0AGXFjB1Hlk8li2Ra1QcdOthJvJTZmSJnEmEfrvndIq4urce_g4cA4h15xNZKLU48YUehKx9IQMeRqLQEQJO_1zD8iFcxvGVCoVPycDwbyGKhmSjzfo0NZQUagLWmNTQ-cfh7ZpLX5BhbVG2pR0gS10pjOOzqjrbQnehroza6zpeDFz0_U9NTVdWdM2lXmgS5Pv4JKclVA5vDrqiKyen1bzRbB8f3mdT5eBlpx1AehEoSpzzVnKEKKCc65CyBHSWAoQmHOlRR7pqEDvRaiiIi8llFCmMgQ5IneH2NY2nz26Ltsap7GqwBfqXRZLKUMR-rARuf1Hbpp-X99lQkVMpEzF3FPjA6Vt45zFMmut2YLdZZxl-8Gz_eCZH9yjN8fAPt9i8Qv-LCy_AZb5e6c</recordid><startdate>20100329</startdate><enddate>20100329</enddate><creator>El-Magrahe, Hamida</creator><creator>Furarah, Abdul Rahaman</creator><creator>El-Figih, Kheiria</creator><creator>El-Urshfany, Sued</creator><creator>Ghenghesh, Khalifa Sifaw</creator><general>Journal of Infection in Developing Countries</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8C1</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20100329</creationdate><title>Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya</title><author>El-Magrahe, Hamida ; Furarah, Abdul Rahaman ; El-Figih, Kheiria ; El-Urshfany, Sued ; Ghenghesh, Khalifa Sifaw</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c310t-ac85e5fbc1090ea6d11154abea9732a2eb15c2b6c6deea96e56dbf3afaf934a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Female</topic><topic>Hepatitis B</topic><topic>Hepatitis B Surface Antigens - immunology</topic><topic>Hepatitis B virus - immunology</topic><topic>Hepatitis B, Chronic - epidemiology</topic><topic>Hepatitis B, Chronic - etiology</topic><topic>Hepatitis B, Chronic - prevention & control</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infectious Disease Transmission, Vertical</topic><topic>Libya - epidemiology</topic><topic>Post-Exposure Prophylaxis</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - epidemiology</topic><topic>Pregnancy Complications, Infectious - etiology</topic><topic>Pregnancy Complications, Infectious - prevention & control</topic><topic>Prevalence</topic><topic>Seroepidemiologic Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El-Magrahe, Hamida</creatorcontrib><creatorcontrib>Furarah, Abdul Rahaman</creatorcontrib><creatorcontrib>El-Figih, Kheiria</creatorcontrib><creatorcontrib>El-Urshfany, Sued</creatorcontrib><creatorcontrib>Ghenghesh, Khalifa Sifaw</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Public Health Database</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of infection in developing countries</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Magrahe, Hamida</au><au>Furarah, Abdul Rahaman</au><au>El-Figih, Kheiria</au><au>El-Urshfany, Sued</au><au>Ghenghesh, Khalifa Sifaw</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya</atitle><jtitle>Journal of infection in developing countries</jtitle><addtitle>J Infect Dev Ctries</addtitle><date>2010-03-29</date><risdate>2010</risdate><volume>4</volume><issue>3</issue><spage>168</spage><epage>170</epage><pages>168-170</pages><issn>1972-2680</issn><issn>2036-6590</issn><eissn>1972-2680</eissn><abstract>Pregnant women with Hepatitis B virus HBV represent a major reservoir of the virus in the community. Data regarding the prevalence of HBV in pregnant women and maternal transmission of the virus in Libya are lacking.
Hepatitis blood samples from 1,500 pregnant women and 1,500 cord blood samples of their neonates delivered at Tripoli Medical Center, Tripoli, were tested for HBsAg by ELISA technique. HBsAg-positive samples were also tested for HBeAg.
HBsAg was detected in 1.5% (23/1,500) pregnant women and in 0.9% (14/1,500) neonates. Although HBsAg was detected at higher rate in pregnant women aged > 25 years [1.8% (22/1,235)] than in pregnant women aged < 25 years [0.4% (1/265)], the difference was not statistically significant (P > 0.05). All HBsAg-positive neonates were born to HBsAg-positive mothers with a rate of maternal transmission at 60.9% (14/23). HBeAg was detected in 21.7% (5/23) and in 7.1% (1/14) of HBsAg-positive pregnant women and neonates, respectively.
Because of the high risk of developing chronic HBV infection at birth among infants born to HBsAg-positive mothers, administration of HBIG in combination with hepatitis B vaccine as post-exposure prophylaxis for such infants is of paramount importance. In addition, universal HBsAg screening of all pregnant women will greatly assist in reducing the maternal transmission of HBV in the country.</abstract><cop>Italy</cop><pub>Journal of Infection in Developing Countries</pub><pmid>20351458</pmid><doi>10.3855/jidc.609</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1972-2680 |
| ispartof | Journal of infection in developing countries, 2010-03, Vol.4 (3), p.168-170 |
| issn | 1972-2680 2036-6590 1972-2680 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_733342497 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Age Factors Female Hepatitis B Hepatitis B Surface Antigens - immunology Hepatitis B virus - immunology Hepatitis B, Chronic - epidemiology Hepatitis B, Chronic - etiology Hepatitis B, Chronic - prevention & control Humans Infant, Newborn Infectious Disease Transmission, Vertical Libya - epidemiology Post-Exposure Prophylaxis Pregnancy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - etiology Pregnancy Complications, Infectious - prevention & control Prevalence Seroepidemiologic Studies |
| title | Maternal and neonatal seroprevalence of Hepatitis B surface antigen (HBsAg) in Tripoli, Libya |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T06%3A24%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Maternal%20and%20neonatal%20seroprevalence%20of%20Hepatitis%20B%20surface%20antigen%20(HBsAg)%20in%20Tripoli,%20Libya&rft.jtitle=Journal%20of%20infection%20in%20developing%20countries&rft.au=El-Magrahe,%20Hamida&rft.date=2010-03-29&rft.volume=4&rft.issue=3&rft.spage=168&rft.epage=170&rft.pages=168-170&rft.issn=1972-2680&rft.eissn=1972-2680&rft_id=info:doi/10.3855/jidc.609&rft_dat=%3Cproquest_cross%3E733342497%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2560290571&rft_id=info:pmid/20351458&rfr_iscdi=true |