Dynamic manipulation and patterning of microparticles and cells by using TiOPc-based optoelectronic dielectrophoresis

We develop light-driven optoelectronic tweezers based on the organic photoconductive material titanium oxide phthalocyanine. These tweezers function based on negative dielectrophoresis (nDEP). The dynamic manipulation of a single microparticle and cell patterning are demonstrated by using this light...

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Veröffentlicht in:Optics letters 2010-06, Vol.35 (12), p.1959-1961
Hauptverfasser: YANG, Shih-Mo, YU, Tung-Ming, HUANG, Hang-Ping, KU, Meng-Yen, HSU, Long, LIU, Cheng-Hsien
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container_end_page 1961
container_issue 12
container_start_page 1959
container_title Optics letters
container_volume 35
creator YANG, Shih-Mo
YU, Tung-Ming
HUANG, Hang-Ping
KU, Meng-Yen
HSU, Long
LIU, Cheng-Hsien
description We develop light-driven optoelectronic tweezers based on the organic photoconductive material titanium oxide phthalocyanine. These tweezers function based on negative dielectrophoresis (nDEP). The dynamic manipulation of a single microparticle and cell patterning are demonstrated by using this light-driven optoelectronic DEP chip. The adaptive light patterns that drive the optoelectronic DEP onchip are designed by using Flash software to approach appropriate dynamic manipulation. This is also the first reported demonstration, to the best of our knowledge, for successfully patterning such delicate cells from human hepatocellular liver carcinoma cell line HepG2 by using any optoelectronic tweezers.
doi_str_mv 10.1364/ol.35.001959
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source OSA Publishing; MEDLINE
subjects Applied sciences
Carcinoma, Hepatocellular - pathology
Cell Line, Tumor
Cell Separation - instrumentation
Electronics
Electrophoresis, Microchip - methods
Equipment Design
Exact sciences and technology
Humans
Instruments, apparatus, components and techniques common to several branches of physics and astronomy
Light
Liver Neoplasms - pathology
Mechanical instruments, equipment and techniques
Micro- and nanoelectromechanical devices (mems/nems)
Micromanipulation - instrumentation
Micromechanical devices and systems
Optical Devices
Optical Tweezers
Physics
Semiconductor electronics. Microelectronics. Optoelectronics. Solid state devices
Titanium - chemistry
title Dynamic manipulation and patterning of microparticles and cells by using TiOPc-based optoelectronic dielectrophoresis
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