Cytomegalovirus-associated superior mesenteric vein thrombosis treated with systemic and in-situ thrombolysis
A 56-year-old patient, first diagnosed with an acute cytomegalovirus infection, presented with progressive abdominal pain because of a superior mesenteric vein thrombosis for which he was treated with systemic thrombolysis and heparin in continuous infusion. As this therapy did not have the intended...
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| Veröffentlicht in: | European journal of gastroenterology & hepatology 2009-05, Vol.21 (5), p.587-592 |
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| container_title | European journal of gastroenterology & hepatology |
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| creator | Moerkercke, Wouter Van Pauwelyn, Karen Brugman, Eddy Verhamme, Marc |
| description | A 56-year-old patient, first diagnosed with an acute cytomegalovirus infection, presented with progressive abdominal pain because of a superior mesenteric vein thrombosis for which he was treated with systemic thrombolysis and heparin in continuous infusion. As this therapy did not have the intended success after 5 days, an interventional radiological procedure was performed with local thrombolysis in the superior mesenteric artery resulting in recanalisation of the vein. Oral anticoagulation was initiated and continued for a period of 6 months. Mesenteric venous thrombosis is a relatively uncommon cause of mesenteric ischemia that can be associated with severe morbidity and significant mortality. With noninvasive techniques, it is possible to establish a diagnosis in the majority of the cases. The importance of an early diagnosis and therapy – not only with anticoagulation, but also thrombolysis in selected cases – is shown with this case and review of the literature. |
| doi_str_mv | 10.1097/MEG.0b013e3283196b15 |
| format | Article |
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As this therapy did not have the intended success after 5 days, an interventional radiological procedure was performed with local thrombolysis in the superior mesenteric artery resulting in recanalisation of the vein. Oral anticoagulation was initiated and continued for a period of 6 months. Mesenteric venous thrombosis is a relatively uncommon cause of mesenteric ischemia that can be associated with severe morbidity and significant mortality. With noninvasive techniques, it is possible to establish a diagnosis in the majority of the cases. 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Diseases of the vena cava. Miscellaneous</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Injections, Intralesional</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mesenteric Vascular Occlusion - drug therapy</subject><subject>Mesenteric Vascular Occlusion - virology</subject><subject>Mesenteric Veins</subject><subject>Middle Aged</subject><subject>Recombinant Proteins - administration & dosage</subject><subject>Thrombolytic Therapy - methods</subject><subject>Tissue Plasminogen Activator - administration & dosage</subject><subject>Venous Thrombosis - drug therapy</subject><subject>Venous Thrombosis - virology</subject><subject>Viral diseases</subject><issn>0954-691X</issn><issn>1473-5687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90EGP1CAUwHFiNO64-g2M6cV46soDCuVoJruryRovmnhrKH110LaMPLqT-faiM2riwRMcfo9H_ow9B34F3JrX769vr3jPQaIUrQSre2gesA0oI-tGt-Yh23DbqFpb-HzBnhB95RyMBPOYXYCVRlrTbNi8PeY44xc3xfuQVqodUfTBZRwqWveYQkzVjIRLLndf3WNYqrxLce4jBapywl_2EPKuoiNlnItyy1CFpaaQ1994Ohb-lD0a3UT47Hxesk831x-3b-u7D7fvtm_uaq8kNHVrhRqkt-j14BzvvQdh9cCHVo0WAITgbT82qm05aG6tEogapB0Mt1p6IS_Zq9O7-xS_r0i5mwN5nCa3YFypM1JKoZVuilQn6VMkSjh2-xRml44d8O5n56507v7tXMZenBes_YzD36Fz2AJenoEj76YxucUH-uMEqLIfdHHtyR3iVArTt2k9YOp26Ka8-_8ffgDKK5qa</recordid><startdate>200905</startdate><enddate>200905</enddate><creator>Moerkercke, Wouter Van</creator><creator>Pauwelyn, Karen</creator><creator>Brugman, Eddy</creator><creator>Verhamme, Marc</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200905</creationdate><title>Cytomegalovirus-associated superior mesenteric vein thrombosis treated with systemic and in-situ thrombolysis</title><author>Moerkercke, Wouter Van ; Pauwelyn, Karen ; Brugman, Eddy ; Verhamme, Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4315-8924d3c9ec6daa0bcc1296d0d84f91112208bf548801609942ee6139d70963c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Cytomegalovirus Infections - complications</topic><topic>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</topic><topic>Gastroenterology. Liver. Pancreas. 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| ispartof | European journal of gastroenterology & hepatology, 2009-05, Vol.21 (5), p.587-592 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cytomegalovirus Infections - complications Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Gastroenterology. Liver. Pancreas. Abdomen Humans Infectious diseases Injections, Intralesional Male Medical sciences Mesenteric Vascular Occlusion - drug therapy Mesenteric Vascular Occlusion - virology Mesenteric Veins Middle Aged Recombinant Proteins - administration & dosage Thrombolytic Therapy - methods Tissue Plasminogen Activator - administration & dosage Venous Thrombosis - drug therapy Venous Thrombosis - virology Viral diseases |
| title | Cytomegalovirus-associated superior mesenteric vein thrombosis treated with systemic and in-situ thrombolysis |
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