Serum Uric Acid Levels and Renal Damage in Hyperuricemic Hypertensive Patients Treated With Renin–Angiotensin System Blockers

Background A correlation between hyperuricemia and renal target organ damage (TOD) was shown in hypertensive patients, locally mediated by the activation of renin–angiotensin system (RAS). We investigated whether high serum uric acid (UA) levels could negatively affect tubulointerstitial damage in h...

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Veröffentlicht in:	American journal of hypertension 2010-06, Vol.23 (6), p.675-680
Hauptverfasser:	Berni, Andrea, Boddi, Maria, Fattori, Elisa Bissoni, Cecioni, Ilaria, Berardino, Sabino, Montuschi, Francesca, Chiostri, Marco, Poggesi, Loredana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged allopurinol Allopurinol - pharmacology Angiotensin II Type 1 Receptor Blockers - therapeutic use Angiotensin-Converting Enzyme Inhibitors - therapeutic use Antihypertensive agents Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels blood pressure Cardiology. Vascular system Cardiovascular system Cross-Sectional Studies Female Humans hypertension Hypertension - blood Hypertension - complications Hypertension - drug therapy Hyperuricemia - blood Hyperuricemia - complications Hyperuricemia - drug therapy Kidney - physiopathology Male Medical sciences Middle Aged Pharmacology. Drug treatments Regression Analysis renal resistive index Renin-Angiotensin System - drug effects renin–angiotensin system serum uric acid Uric Acid - blood
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