Change in I-123 Uptake by a Hyperfunctioning Thyroid Nodule in a Patient With Multinodular Goiter and Subclinical Hyperthyroidism
Multinodular goiter is characterized by heterogeneous thyroid growth that results in one or more dominant nodules superimposed on many nonpalpable ones. Over time, nodules display slow growth, stasis, or regression, and variable iodine uptake on nuclear imaging. Subclinical hyperthyroidism is charac...
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Veröffentlicht in: | Clinical nuclear medicine 2010-06, Vol.35 (6), p.440-442 |
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description | Multinodular goiter is characterized by heterogeneous thyroid growth that results in one or more dominant nodules superimposed on many nonpalpable ones. Over time, nodules display slow growth, stasis, or regression, and variable iodine uptake on nuclear imaging. Subclinical hyperthyroidism is characterized by suppressed TSH, normal free T3 and T4, and variable expression of signs and symptoms of hyperthyroidism. The case of a dominant hot nodule within a multinodular goiter representing a hyperplastic colloid nodule or nonautonomous hyperfunctioning (follicular) adenoma producing subclinical hyperthyroidism that subsequently became cold with normalization of TSH is presented. |
doi_str_mv | 10.1097/RLU.0b013e3181db4c83 |
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The case of a dominant hot nodule within a multinodular goiter representing a hyperplastic colloid nodule or nonautonomous hyperfunctioning (follicular) adenoma producing subclinical hyperthyroidism that subsequently became cold with normalization of TSH is presented.</description><identifier>ISSN: 0363-9762</identifier><identifier>EISSN: 1536-0229</identifier><identifier>DOI: 10.1097/RLU.0b013e3181db4c83</identifier><identifier>PMID: 20479596</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Biological Transport ; Female ; Goiter - complications ; Humans ; Hyperthyroidism - complications ; Iodine Radioisotopes - metabolism ; Middle Aged ; Thyroid Nodule - complications ; Thyroid Nodule - diagnosis ; Thyroid Nodule - metabolism ; Thyroid Nodule - physiopathology</subject><ispartof>Clinical nuclear medicine, 2010-06, Vol.35 (6), p.440-442</ispartof><rights>2010 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3005-bdb072c69121ce2c888b1205700687e821ca9f23d76150b0994c5010f78111f03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20479596$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Achong, Dwight M</creatorcontrib><title>Change in I-123 Uptake by a Hyperfunctioning Thyroid Nodule in a Patient With Multinodular Goiter and Subclinical Hyperthyroidism</title><title>Clinical nuclear medicine</title><addtitle>Clin Nucl Med</addtitle><description>Multinodular goiter is characterized by heterogeneous thyroid growth that results in one or more dominant nodules superimposed on many nonpalpable ones. 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The case of a dominant hot nodule within a multinodular goiter representing a hyperplastic colloid nodule or nonautonomous hyperfunctioning (follicular) adenoma producing subclinical hyperthyroidism that subsequently became cold with normalization of TSH is presented.</description><subject>Biological Transport</subject><subject>Female</subject><subject>Goiter - complications</subject><subject>Humans</subject><subject>Hyperthyroidism - complications</subject><subject>Iodine Radioisotopes - metabolism</subject><subject>Middle Aged</subject><subject>Thyroid Nodule - complications</subject><subject>Thyroid Nodule - diagnosis</subject><subject>Thyroid Nodule - metabolism</subject><subject>Thyroid Nodule - physiopathology</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU2PFCEQhonRuOPqPzCGm6deq6Cbbo5morubjB_RnXgkNE1v4zL0CHQ2c_SfyzirJlZCKlD1vsBThLxEuECQ7Zsvm-0F9IDccuxw6GvT8UdkhQ0XFTAmH5MVcMEr2Qp2Rp6l9B0ABYr6KTljULeykWJFfq4nHW4tdYFeV8g43e6zvrO0P1BNrw57G8clmOzm4MItvZkOcXYD_TgPi_8t0vSzzs6GTL-5PNEPi88uHKs60svZZRupDgP9uvTGu-CM9ifXfHJyafecPBm1T_bFQz4n2_fvbtZX1ebT5fX67aYyHKCp-qGHlhkhkaGxzHRd1yODpgUQXWu7cqrlyPjQCmwKFylr0wDC2HaIOAI_J69Pvvs4_1hsymrnkrHe62DnJamWc45CwrGzPnWaOKcU7aj20e10PCgEdWSvCnv1P_sie_VwwdLv7PBX9Af2P9_72Rcw6c4v9zaqyWqfJwUlePlixcqrQZRdVVYZ5y-fx4_-</recordid><startdate>201006</startdate><enddate>201006</enddate><creator>Achong, Dwight M</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201006</creationdate><title>Change in I-123 Uptake by a Hyperfunctioning Thyroid Nodule in a Patient With Multinodular Goiter and Subclinical Hyperthyroidism</title><author>Achong, Dwight M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3005-bdb072c69121ce2c888b1205700687e821ca9f23d76150b0994c5010f78111f03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Biological Transport</topic><topic>Female</topic><topic>Goiter - complications</topic><topic>Humans</topic><topic>Hyperthyroidism - complications</topic><topic>Iodine Radioisotopes - metabolism</topic><topic>Middle Aged</topic><topic>Thyroid Nodule - complications</topic><topic>Thyroid Nodule - diagnosis</topic><topic>Thyroid Nodule - metabolism</topic><topic>Thyroid Nodule - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Achong, Dwight M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Achong, Dwight M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Change in I-123 Uptake by a Hyperfunctioning Thyroid Nodule in a Patient With Multinodular Goiter and Subclinical Hyperthyroidism</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>2010-06</date><risdate>2010</risdate><volume>35</volume><issue>6</issue><spage>440</spage><epage>442</epage><pages>440-442</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><abstract>Multinodular goiter is characterized by heterogeneous thyroid growth that results in one or more dominant nodules superimposed on many nonpalpable ones. 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source | MEDLINE; Journals@Ovid Complete |
subjects | Biological Transport Female Goiter - complications Humans Hyperthyroidism - complications Iodine Radioisotopes - metabolism Middle Aged Thyroid Nodule - complications Thyroid Nodule - diagnosis Thyroid Nodule - metabolism Thyroid Nodule - physiopathology |
title | Change in I-123 Uptake by a Hyperfunctioning Thyroid Nodule in a Patient With Multinodular Goiter and Subclinical Hyperthyroidism |
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