Experimental iron-inactivated Pasteurella multocida A: 1 vaccine adjuvanted with bacterial DNA is safe and protects chickens from fowl cholera

Abstract Fowl cholera is a serious problem in large and small scale poultry production. The present study describes the development and testing of an inactivated whole-cell, low-cost, safe, and effective vaccine for fowl cholera based on a previous work ( Vaccine 23:5590–5598). Pasteurella multocida...

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Veröffentlicht in:	Vaccine 2010-03, Vol.28 (11), p.2284-2289
Hauptverfasser:	Herath, Chitra, Kumar, Pankaj, Singh, Mithilesh, Kumar, Devender, Ramakrishnan, Saravanan, Goswami, Tapas Kumar, Singh, Ajit, Ram, G.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, Immunologic - administration & dosage Adjuvants, Immunologic - adverse effects Allergy and Immunology Animal vaccines Animals Antibodies, Bacterial - blood Applied microbiology Bacteria Bacterial DNA Bacterial Vaccines - adverse effects Bacterial Vaccines - immunology Bacteriology Biological and medical sciences Chickens CpG motifs Deoxyribonucleic acid Developing countries DNA DNA, Bacterial - administration & dosage DNA, Bacterial - adverse effects Ferric chloride Fowl cholera Fundamental and applied biological sciences. Psychology Immune system Immunization Immunization, Secondary - methods Immunoglobulins - blood LDCs Microbiology Miscellaneous Overdose Pasteurella Infections - prevention & control Pasteurella Infections - veterinary Pasteurella multocida Pasteurella multocida - immunology Pasteurella multocida A: 1 Pathology Poultry Poultry Diseases - immunology Poultry Diseases - prevention & control Poultry production Survival Analysis Vaccination - methods Vaccine Vaccine safety Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Inactivated - adverse effects Vaccines, Inactivated - immunology Waterborne diseases
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