Incorporating time postinoculation into a dose-response model of Yersinia pestis in mice

To develop a time-dependent dose-response model for describing the survival of animals exposed to Yersinia pestis. Candidate time-dependent dose-response models were fitted to a survival data set for mice intraperitoneally exposed to graded doses of Y. pestis using the maximum likelihood estimation...

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Veröffentlicht in:	Journal of applied microbiology 2009-09, Vol.107 (3), p.727-735
Hauptverfasser:	Huang, Y, Bartrand, T.A, Haas, C.N, Weir, M.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences chi-squared Colony Count, Microbial Disease Models, Animal dose-response model Fundamental and applied biological sciences. Psychology maximum likelihood estimation Mice Mice, Inbred BALB C Microbiology mortality plague Plague - mortality survival Survival Analysis Time Factors time postinoculation Yersinia pestis Yersinia pestis - growth & development
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