Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis

Abstract Prostaglandin E2 (PGE2 ) and prostaglandin E (EP) receptor signaling pathways have been implicated in the promotion of tumor growth and angiogenesis. However, little is known about their roles in lymphangiogenesis during tumor development. The present study evaluates whether endogenous PGE2...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomedicine & pharmacotherapy 2010-02, Vol.64 (2), p.101-106
Hauptverfasser:	Kubo, Hidefumi, Hosono, Kanako, Suzuki, Tatsunori, Ogawa, Yasufumi, Kato, Hiroshi, Kamata, Hiroki, Ito, Yoshiya, Amano, Hideki, Kato, Tetsuki, Sakagami, Hiroyuki, Hayashi, Izumi, Sugimoto, Yukihiko, Narumiya, Shuh, Watanabe, Masahiko, Majima, Masataka
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cancer Celecoxib Cell Line, Tumor COX-2 Cyclooxygenase 2 Inhibitors - pharmacology Cyclooxygenase 2 Inhibitors - therapeutic use Eicosanoid Gene Expression Regulation, Neoplastic - drug effects Internal Medicine Lymphangiogenesis - drug effects Lymphangiogenesis - physiology Male Medical Education Medical sciences Membrane Glycoproteins - metabolism Mice Mice, Knockout Neoplasms - drug therapy Neoplasms - metabolism Pharmacology. Drug treatments Pyrazoles - pharmacology Pyrazoles - therapeutic use Receptors, Prostaglandin E - antagonists & inhibitors Receptors, Prostaglandin E - genetics Receptors, Prostaglandin E - metabolism Receptors, Prostaglandin E - physiology Receptors, Vascular Endothelial Growth Factor - drug effects Receptors, Vascular Endothelial Growth Factor - metabolism Receptors, Vascular Endothelial Growth Factor - physiology Signal Transduction - drug effects Sulfonamides - pharmacology Sulfonamides - therapeutic use Tumor Burden - drug effects VEGF-C VEGFR-3 Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!