Paradoxical Hypertrichosis After Laser Therapy: A Review

BACKGROUND Laser hair removal is a safe and effective procedure for the treatment of unwanted body hair but is not exempt from side effects. A rare but significant adverse effect with this treatment modality is paradoxical hypertrichosis. OBJECTIVE To evaluate the potential etiologies, risk factors,...

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Veröffentlicht in:Dermatologic surgery 2010-03, Vol.36 (3), p.291-298
Hauptverfasser: DESAI, SHRADDHA, MAHMOUD, BASSEL H., BHATIA, ASHISH C., HAMZAVI, ILTEFAT H.
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container_end_page 298
container_issue 3
container_start_page 291
container_title Dermatologic surgery
container_volume 36
creator DESAI, SHRADDHA
MAHMOUD, BASSEL H.
BHATIA, ASHISH C.
HAMZAVI, ILTEFAT H.
description BACKGROUND Laser hair removal is a safe and effective procedure for the treatment of unwanted body hair but is not exempt from side effects. A rare but significant adverse effect with this treatment modality is paradoxical hypertrichosis. OBJECTIVE To evaluate the potential etiologies, risk factors, related laser types, and treatment options for the development of excess hair after laser therapy. MATERIALS AND METHODS An analysis of previously published case studies and review articles along with our own experience was used to gather information regarding this phenomenon. RESULTS Paradoxical hypertrichosis has a low incidence, ranging from 0.6% to 10%, and most commonly occurs on the face and neck. All laser and light sources have the potential to cause hair induction, especially in individuals with darker skin types (III–VI); with dark, thick hair; and with underlying hormonal conditions. Possible causes include the effect of inflammatory mediators and subtherapeutic thermal injury causing induction of the hair cycle. Treatment for paradoxical hypertrichosis is laser therapy of the affected area. CONCLUSIONS Paradoxical hypertrichosis is a rare side effect of laser hair removal; the pathogenesis of this event remains widely unknown. We recommend further large‐scale studies to investigate this effect. The authors have indicated no significant interest with commercial supporters.
doi_str_mv 10.1111/j.1524-4725.2009.01433.x
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A rare but significant adverse effect with this treatment modality is paradoxical hypertrichosis. OBJECTIVE To evaluate the potential etiologies, risk factors, related laser types, and treatment options for the development of excess hair after laser therapy. MATERIALS AND METHODS An analysis of previously published case studies and review articles along with our own experience was used to gather information regarding this phenomenon. RESULTS Paradoxical hypertrichosis has a low incidence, ranging from 0.6% to 10%, and most commonly occurs on the face and neck. All laser and light sources have the potential to cause hair induction, especially in individuals with darker skin types (III–VI); with dark, thick hair; and with underlying hormonal conditions. Possible causes include the effect of inflammatory mediators and subtherapeutic thermal injury causing induction of the hair cycle. Treatment for paradoxical hypertrichosis is laser therapy of the affected area. CONCLUSIONS Paradoxical hypertrichosis is a rare side effect of laser hair removal; the pathogenesis of this event remains widely unknown. We recommend further large‐scale studies to investigate this effect. The authors have indicated no significant interest with commercial supporters.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1111/j.1524-4725.2009.01433.x</identifier><identifier>PMID: 20100274</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Biological and medical sciences ; Dermatology ; Hair and nails disorders ; Hair Follicle - injuries ; Hair Follicle - physiopathology ; Hair Removal - adverse effects ; Hair Removal - methods ; Humans ; Hypertrichosis - epidemiology ; Hypertrichosis - etiology ; Hypertrichosis - physiopathology ; Laser Therapy - adverse effects ; Medical sciences ; Risk Factors ; Skin plastic surgery ; Surgery (general aspects). 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A rare but significant adverse effect with this treatment modality is paradoxical hypertrichosis. OBJECTIVE To evaluate the potential etiologies, risk factors, related laser types, and treatment options for the development of excess hair after laser therapy. MATERIALS AND METHODS An analysis of previously published case studies and review articles along with our own experience was used to gather information regarding this phenomenon. RESULTS Paradoxical hypertrichosis has a low incidence, ranging from 0.6% to 10%, and most commonly occurs on the face and neck. All laser and light sources have the potential to cause hair induction, especially in individuals with darker skin types (III–VI); with dark, thick hair; and with underlying hormonal conditions. Possible causes include the effect of inflammatory mediators and subtherapeutic thermal injury causing induction of the hair cycle. Treatment for paradoxical hypertrichosis is laser therapy of the affected area. 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source MEDLINE; Journals@Ovid Complete; Access via Wiley Online Library
subjects Biological and medical sciences
Dermatology
Hair and nails disorders
Hair Follicle - injuries
Hair Follicle - physiopathology
Hair Removal - adverse effects
Hair Removal - methods
Humans
Hypertrichosis - epidemiology
Hypertrichosis - etiology
Hypertrichosis - physiopathology
Laser Therapy - adverse effects
Medical sciences
Risk Factors
Skin plastic surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
title Paradoxical Hypertrichosis After Laser Therapy: A Review
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