SHORT LIFE EXPECTANCY AND METABOLIC SYNDROME IN ROMANIES (GYPSIES) IN SLOVAKIA
The aim of this review is to explain short life expectancy in Romanies. Romanies represent the second largest minority in Slovakia (about 7%). Most of them exist on the fringes of the majority society. Their general situation worsened after the fall of communism in 1989. In a market oriented society...
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description | The aim of this review is to explain short life expectancy in Romanies. Romanies represent the second largest minority in Slovakia (about 7%). Most of them exist on the fringes of the majority society. Their general situation worsened after the fall of communism in 1989. In a market oriented society the unemployment of Romanies further increased due to their poor education and lack of skills. Romany general health is substantially worse than that of the majority population: They have high prevalence of communicable diseases due to poor sanitary and living conditions. Furthermore, epidemiological and metabolic studies revealed in Romanies high prevalence of obesity associated with increased cardiovascular risk. There is no explanation for this seemingly paradoxical phenomenon, in a population living in poor economic conditions. It is possible that in the course of the many generation-long migration from India to Europe, pregnant Romanies and their fetuses sufferred excessive nutritional deficiency. This might have induced adaptive metabolic and genetic changes aimed at optimum utilization of scarce food supply. There is a hypothetical possibility that in them "thrifty gene" was formed. Arrival of Romanies to Europe resulted in somewhat better nutrition, along with sharply reduced physical expenditure. The consequence is a metabolic syndrome with type 2 diabetes and increased cardiovascular mortality. Such unique metabolic feature in Romanies will undoubtedly stimulate further research in molecular biology that may ultimately clarify the role of "thrifty genes". |
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Romanies represent the second largest minority in Slovakia (about 7%). Most of them exist on the fringes of the majority society. Their general situation worsened after the fall of communism in 1989. In a market oriented society the unemployment of Romanies further increased due to their poor education and lack of skills. Romany general health is substantially worse than that of the majority population: They have high prevalence of communicable diseases due to poor sanitary and living conditions. Furthermore, epidemiological and metabolic studies revealed in Romanies high prevalence of obesity associated with increased cardiovascular risk. There is no explanation for this seemingly paradoxical phenomenon, in a population living in poor economic conditions. It is possible that in the course of the many generation-long migration from India to Europe, pregnant Romanies and their fetuses sufferred excessive nutritional deficiency. This might have induced adaptive metabolic and genetic changes aimed at optimum utilization of scarce food supply. There is a hypothetical possibility that in them "thrifty gene" was formed. Arrival of Romanies to Europe resulted in somewhat better nutrition, along with sharply reduced physical expenditure. The consequence is a metabolic syndrome with type 2 diabetes and increased cardiovascular mortality. Such unique metabolic feature in Romanies will undoubtedly stimulate further research in molecular biology that may ultimately clarify the role of "thrifty genes".</description><identifier>ISSN: 1210-7778</identifier><identifier>EISSN: 1803-1048</identifier><identifier>DOI: 10.21101/cejph.b0011</identifier><identifier>PMID: 20586225</identifier><language>eng</language><publisher>Prague: National Institute of Public Health</publisher><subject>Biological and medical sciences ; Cardiovascular disease ; Diabetes ; Economic conditions ; Female ; Food supply ; Genetic Predisposition to Disease ; Health risks ; Humans ; Infant mortality ; Life expectancy ; Life Expectancy - ethnology ; Living conditions ; Low income groups ; Male ; Males ; Medical sciences ; Metabolic diseases ; Metabolic disorders ; Metabolic Syndrome - epidemiology ; Metabolic Syndrome - ethnology ; Metabolic Syndrome - genetics ; Miscellaneous ; Molecular biology ; Obesity ; Older people ; Other metabolic disorders ; Phenotype ; Public health. 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Romanies represent the second largest minority in Slovakia (about 7%). Most of them exist on the fringes of the majority society. Their general situation worsened after the fall of communism in 1989. In a market oriented society the unemployment of Romanies further increased due to their poor education and lack of skills. Romany general health is substantially worse than that of the majority population: They have high prevalence of communicable diseases due to poor sanitary and living conditions. Furthermore, epidemiological and metabolic studies revealed in Romanies high prevalence of obesity associated with increased cardiovascular risk. There is no explanation for this seemingly paradoxical phenomenon, in a population living in poor economic conditions. It is possible that in the course of the many generation-long migration from India to Europe, pregnant Romanies and their fetuses sufferred excessive nutritional deficiency. This might have induced adaptive metabolic and genetic changes aimed at optimum utilization of scarce food supply. There is a hypothetical possibility that in them "thrifty gene" was formed. Arrival of Romanies to Europe resulted in somewhat better nutrition, along with sharply reduced physical expenditure. The consequence is a metabolic syndrome with type 2 diabetes and increased cardiovascular mortality. Such unique metabolic feature in Romanies will undoubtedly stimulate further research in molecular biology that may ultimately clarify the role of "thrifty genes".</description><subject>Biological and medical sciences</subject><subject>Cardiovascular disease</subject><subject>Diabetes</subject><subject>Economic conditions</subject><subject>Female</subject><subject>Food supply</subject><subject>Genetic Predisposition to Disease</subject><subject>Health risks</subject><subject>Humans</subject><subject>Infant mortality</subject><subject>Life expectancy</subject><subject>Life Expectancy - ethnology</subject><subject>Living conditions</subject><subject>Low income groups</subject><subject>Male</subject><subject>Males</subject><subject>Medical sciences</subject><subject>Metabolic diseases</subject><subject>Metabolic disorders</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Metabolic Syndrome - ethnology</subject><subject>Metabolic Syndrome - genetics</subject><subject>Miscellaneous</subject><subject>Molecular biology</subject><subject>Obesity</subject><subject>Older people</subject><subject>Other metabolic disorders</subject><subject>Phenotype</subject><subject>Public health. 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Romanies represent the second largest minority in Slovakia (about 7%). Most of them exist on the fringes of the majority society. Their general situation worsened after the fall of communism in 1989. In a market oriented society the unemployment of Romanies further increased due to their poor education and lack of skills. Romany general health is substantially worse than that of the majority population: They have high prevalence of communicable diseases due to poor sanitary and living conditions. Furthermore, epidemiological and metabolic studies revealed in Romanies high prevalence of obesity associated with increased cardiovascular risk. There is no explanation for this seemingly paradoxical phenomenon, in a population living in poor economic conditions. It is possible that in the course of the many generation-long migration from India to Europe, pregnant Romanies and their fetuses sufferred excessive nutritional deficiency. This might have induced adaptive metabolic and genetic changes aimed at optimum utilization of scarce food supply. There is a hypothetical possibility that in them "thrifty gene" was formed. Arrival of Romanies to Europe resulted in somewhat better nutrition, along with sharply reduced physical expenditure. The consequence is a metabolic syndrome with type 2 diabetes and increased cardiovascular mortality. Such unique metabolic feature in Romanies will undoubtedly stimulate further research in molecular biology that may ultimately clarify the role of "thrifty genes".</abstract><cop>Prague</cop><pub>National Institute of Public Health</pub><pmid>20586225</pmid><doi>10.21101/cejph.b0011</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Biological and medical sciences Cardiovascular disease Diabetes Economic conditions Female Food supply Genetic Predisposition to Disease Health risks Humans Infant mortality Life expectancy Life Expectancy - ethnology Living conditions Low income groups Male Males Medical sciences Metabolic diseases Metabolic disorders Metabolic Syndrome - epidemiology Metabolic Syndrome - ethnology Metabolic Syndrome - genetics Miscellaneous Molecular biology Obesity Older people Other metabolic disorders Phenotype Public health. Hygiene Public health. Hygiene-occupational medicine Roma Slovakia - epidemiology |
title | SHORT LIFE EXPECTANCY AND METABOLIC SYNDROME IN ROMANIES (GYPSIES) IN SLOVAKIA |
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