Nuclear inositide signaling in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are defined as clonal hematopoietic stem‐cell disorders characterized by ineffective hematopoiesis in one or more of the lineages of the bone marrow. Although distinct morphologic subgroups exist, the natural history of MDS is progression to acute myeloid leukemia (AM...

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Veröffentlicht in:	Journal of cellular biochemistry 2010-04, Vol.109 (6), p.1065-1071
Hauptverfasser:	Follo, Matilde Y., Mongiorgi, Sara, Finelli, Carlo, Clissa, Cristina, Ramazzotti, Giulia, Fiume, Roberta, Faenza, Irene, Manzoli, Lucia, Martelli, Alberto M., Cocco, Lucio
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt Animals Cell Nucleus - metabolism Humans Leukemia, Myeloid, Acute - metabolism Leukemia, Myeloid, Acute - pathology myelodysplastic syndromes Myelodysplastic Syndromes - metabolism Myelodysplastic Syndromes - physiopathology nucleus Phosphatidylinositols - metabolism Phospholipase C beta - metabolism PI-PLCbeta1 Proto-Oncogene Proteins c-akt - metabolism signal transduction Signal Transduction - physiology
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