Lobular carcinoma in situ variants in breast cores: potential for misdiagnosis, upgrade rates at surgical excision, and practical implications

Differentiating ductal carcinoma in situ (DCIS) from lobular carcinoma in situ (LCIS) on core biopsy has important clinical implications. Lobular carcinoma in situ variants, including LCIS with necrosis and pleomorphic LCIS, share morphologic features with solid DCIS that may lead to misclassificati...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) 2010-07, Vol.134 (7), p.1024-1028
Hauptverfasser:	Sullivan, Megan E, Khan, Seema A, Sullu, Yurdanur, Schiller, Carol, Susnik, Barbara
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Breast - pathology Breast Neoplasms - chemistry Breast Neoplasms - pathology Breast Neoplasms - surgery Cadherins - analysis Carcinoma in Situ - chemistry Carcinoma in Situ - pathology Carcinoma in Situ - surgery Carcinoma, Ductal, Breast - pathology Carcinoma, Lobular - chemistry Carcinoma, Lobular - pathology Carcinoma, Lobular - surgery Diagnosis, Differential Diagnostic Errors - statistics & numerical data Female Humans Necrosis Neoplasm Invasiveness Neoplasm Staging
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