Stilbene analogs as inducers of apolipoprotein-I transcription

Based on the naturally occurring stilbene, Resveratrol, a series of novel stilbene derivatives were synthesized, which have the ability to induce the expression of the ApoA-I gene. Several compounds equally or more potent than Resveratrol were identified. trans-4,4′-Dihydroxy-2-methoxystilbene was t...

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Veröffentlicht in:European journal of medicinal chemistry 2010-05, Vol.45 (5), p.2018-2023
Hauptverfasser: Hansen, Henrik C., Chiacchia, Fabrizio S., Patel, Reena, Wong, Norman C.W., Khlebnikov, Vladimir, Jankowska, Renata, Patel, Kalpesh, Reddy, M. Madhava
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Sprache:eng
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