Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors

.  Raiko JRH, Viikari JSA, Ilmanen A, Hutri‐Kähönen N, Taittonen L, Jokinen E, Pietikäinen M, Jula A, Loo B.‐M, Marniemi J, Lehtimäki T, Kähönen M, Rönnemaa T, Raitakari OT, Juonala M (University of Turku; University of Tampere and Tampere University Hospital, Tampere; University of Oulu, Oulu; Vaas...

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Veröffentlicht in:Journal of internal medicine 2010-04, Vol.267 (4), p.370-384
Hauptverfasser: Raiko, J. R. H., Viikari, J. S. A., Ilmanen, A., Hutri‐Kähönen, N., Taittonen, L., Jokinen, E., Pietikäinen, M., Jula, A., Loo, B.‐M., Marniemi, J., Lehtimäki, T., Kähönen, M., Rönnemaa, T., Raitakari, O. T., Juonala, M.
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container_end_page 384
container_issue 4
container_start_page 370
container_title Journal of internal medicine
container_volume 267
creator Raiko, J. R. H.
Viikari, J. S. A.
Ilmanen, A.
Hutri‐Kähönen, N.
Taittonen, L.
Jokinen, E.
Pietikäinen, M.
Jula, A.
Loo, B.‐M.
Marniemi, J.
Lehtimäki, T.
Kähönen, M.
Rönnemaa, T.
Raitakari, O. T.
Juonala, M.
description .  Raiko JRH, Viikari JSA, Ilmanen A, Hutri‐Kähönen N, Taittonen L, Jokinen E, Pietikäinen M, Jula A, Loo B.‐M, Marniemi J, Lehtimäki T, Kähönen M, Rönnemaa T, Raitakari OT, Juonala M (University of Turku; University of Tampere and Tampere University Hospital, Tampere; University of Oulu, Oulu; Vaasa Central Hospital, Vaasa; University of Helsinki, Helsinki; and Center of Social and Health Services, Kuopio; Finland). Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors. J Intern Med 2010; 267: 370–384. Objectives.  To examine cardiovascular risk factor levels in 2007 and their 6‐year changes between 2001 and 2007 using the data collected in the follow‐ups of the Cardiovascular Risk in Young Finns Study. Design.  Population‐based follow‐up study. Subjects.  A total of 2204 healthy Finnish adults aged 30–45 years (1210 women; 994 men). Main outcome measures.  Levels in 2007 and changes between 2001 and 2007 of lipids, insulin, glucose, blood pressure, smoking, body mass index, alcohol consumption, waist and hip circumferences. Results.  The mean serum total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol and triglyceride concentrations in 30‐ to 45‐year‐old adults were 5.05, 3.09, 1.34 and 1.40 mmol L−1, respectively. Significant changes (P 
doi_str_mv 10.1111/j.1365-2796.2009.02148.x
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R. H. ; Viikari, J. S. A. ; Ilmanen, A. ; Hutri‐Kähönen, N. ; Taittonen, L. ; Jokinen, E. ; Pietikäinen, M. ; Jula, A. ; Loo, B.‐M. ; Marniemi, J. ; Lehtimäki, T. ; Kähönen, M. ; Rönnemaa, T. ; Raitakari, O. T. ; Juonala, M.</creator><creatorcontrib>Raiko, J. R. H. ; Viikari, J. S. A. ; Ilmanen, A. ; Hutri‐Kähönen, N. ; Taittonen, L. ; Jokinen, E. ; Pietikäinen, M. ; Jula, A. ; Loo, B.‐M. ; Marniemi, J. ; Lehtimäki, T. ; Kähönen, M. ; Rönnemaa, T. ; Raitakari, O. T. ; Juonala, M.</creatorcontrib><description>.  Raiko JRH, Viikari JSA, Ilmanen A, Hutri‐Kähönen N, Taittonen L, Jokinen E, Pietikäinen M, Jula A, Loo B.‐M, Marniemi J, Lehtimäki T, Kähönen M, Rönnemaa T, Raitakari OT, Juonala M (University of Turku; University of Tampere and Tampere University Hospital, Tampere; University of Oulu, Oulu; Vaasa Central Hospital, Vaasa; University of Helsinki, Helsinki; and Center of Social and Health Services, Kuopio; Finland). Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors. J Intern Med 2010; 267: 370–384. Objectives.  To examine cardiovascular risk factor levels in 2007 and their 6‐year changes between 2001 and 2007 using the data collected in the follow‐ups of the Cardiovascular Risk in Young Finns Study. Design.  Population‐based follow‐up study. Subjects.  A total of 2204 healthy Finnish adults aged 30–45 years (1210 women; 994 men). Main outcome measures.  Levels in 2007 and changes between 2001 and 2007 of lipids, insulin, glucose, blood pressure, smoking, body mass index, alcohol consumption, waist and hip circumferences. Results.  The mean serum total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol and triglyceride concentrations in 30‐ to 45‐year‐old adults were 5.05, 3.09, 1.34 and 1.40 mmol L−1, respectively. Significant changes (P &lt; 0.05) between 2001 and 2007 in 30‐ to 39‐year‐old subjects included a decrease in total cholesterol (−6.6% in men, −5.8% in women), LDL‐cholesterol (−10.2% and −11.6%) and an increase in diastolic blood pressure (3.5% and 3.9%). Waist circumference (1.8% and 5.5%) and systolic blood pressure increased in 36–39 year olds (2.3% and 2.3%). HDL‐cholesterol increased in 30‐ to 33‐year‐old women (5.8%) Glucose levels increased in 30‐ to 39‐year‐old women (3.7%) and 36‐ to 39‐year‐old men (3.6%). Smoking prevalence decreased in 36‐ to 39‐year‐old men from 29.8% to 22.2%. Conclusions.  The 6‐year changes in total cholesterol, LDL‐cholesterol and HDL‐cholesterol in young Finns were favourable between 2001 and 2007. However, waist circumference, glucose and blood pressure levels increased. Therefore, continuous efforts are still needed in fighting against cardiovascular risk factors.</description><identifier>ISSN: 0954-6820</identifier><identifier>EISSN: 1365-2796</identifier><identifier>DOI: 10.1111/j.1365-2796.2009.02148.x</identifier><identifier>PMID: 19754855</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Alcohol Drinking ; Biological and medical sciences ; Blood Glucose ; Blood Pressure - physiology ; Body Mass Index ; cardiovascular ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - physiopathology ; change ; Epidemiology ; Female ; Finland ; Follow-Up Studies ; General aspects ; Humans ; Insulin - blood ; Lipids - blood ; Male ; Medical sciences ; Metabolic Syndrome - epidemiology ; Middle Aged ; Miscellaneous ; Prevalence ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk Factors ; Waist-Hip Ratio</subject><ispartof>Journal of internal medicine, 2010-04, Vol.267 (4), p.370-384</ispartof><rights>2009 Blackwell Publishing Ltd</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4498-a32f0b46c54d6c8765d9628eff53eac8179cecda56bc225f01aafa9ad7daf69a3</citedby><cites>FETCH-LOGICAL-c4498-a32f0b46c54d6c8765d9628eff53eac8179cecda56bc225f01aafa9ad7daf69a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2796.2009.02148.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2796.2009.02148.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,1435,27931,27932,45581,45582,46416,46840</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=22530289$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19754855$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Raiko, J. R. H.</creatorcontrib><creatorcontrib>Viikari, J. S. A.</creatorcontrib><creatorcontrib>Ilmanen, A.</creatorcontrib><creatorcontrib>Hutri‐Kähönen, N.</creatorcontrib><creatorcontrib>Taittonen, L.</creatorcontrib><creatorcontrib>Jokinen, E.</creatorcontrib><creatorcontrib>Pietikäinen, M.</creatorcontrib><creatorcontrib>Jula, A.</creatorcontrib><creatorcontrib>Loo, B.‐M.</creatorcontrib><creatorcontrib>Marniemi, J.</creatorcontrib><creatorcontrib>Lehtimäki, T.</creatorcontrib><creatorcontrib>Kähönen, M.</creatorcontrib><creatorcontrib>Rönnemaa, T.</creatorcontrib><creatorcontrib>Raitakari, O. T.</creatorcontrib><creatorcontrib>Juonala, M.</creatorcontrib><title>Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors</title><title>Journal of internal medicine</title><addtitle>J Intern Med</addtitle><description>.  Raiko JRH, Viikari JSA, Ilmanen A, Hutri‐Kähönen N, Taittonen L, Jokinen E, Pietikäinen M, Jula A, Loo B.‐M, Marniemi J, Lehtimäki T, Kähönen M, Rönnemaa T, Raitakari OT, Juonala M (University of Turku; University of Tampere and Tampere University Hospital, Tampere; University of Oulu, Oulu; Vaasa Central Hospital, Vaasa; University of Helsinki, Helsinki; and Center of Social and Health Services, Kuopio; Finland). Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors. J Intern Med 2010; 267: 370–384. Objectives.  To examine cardiovascular risk factor levels in 2007 and their 6‐year changes between 2001 and 2007 using the data collected in the follow‐ups of the Cardiovascular Risk in Young Finns Study. Design.  Population‐based follow‐up study. Subjects.  A total of 2204 healthy Finnish adults aged 30–45 years (1210 women; 994 men). Main outcome measures.  Levels in 2007 and changes between 2001 and 2007 of lipids, insulin, glucose, blood pressure, smoking, body mass index, alcohol consumption, waist and hip circumferences. Results.  The mean serum total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol and triglyceride concentrations in 30‐ to 45‐year‐old adults were 5.05, 3.09, 1.34 and 1.40 mmol L−1, respectively. Significant changes (P &lt; 0.05) between 2001 and 2007 in 30‐ to 39‐year‐old subjects included a decrease in total cholesterol (−6.6% in men, −5.8% in women), LDL‐cholesterol (−10.2% and −11.6%) and an increase in diastolic blood pressure (3.5% and 3.9%). Waist circumference (1.8% and 5.5%) and systolic blood pressure increased in 36–39 year olds (2.3% and 2.3%). HDL‐cholesterol increased in 30‐ to 33‐year‐old women (5.8%) Glucose levels increased in 30‐ to 39‐year‐old women (3.7%) and 36‐ to 39‐year‐old men (3.6%). Smoking prevalence decreased in 36‐ to 39‐year‐old men from 29.8% to 22.2%. Conclusions.  The 6‐year changes in total cholesterol, LDL‐cholesterol and HDL‐cholesterol in young Finns were favourable between 2001 and 2007. However, waist circumference, glucose and blood pressure levels increased. Therefore, continuous efforts are still needed in fighting against cardiovascular risk factors.</description><subject>Adult</subject><subject>Alcohol Drinking</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose</subject><subject>Blood Pressure - physiology</subject><subject>Body Mass Index</subject><subject>cardiovascular</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - physiopathology</subject><subject>change</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Finland</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Humans</subject><subject>Insulin - blood</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Prevalence</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Risk Factors</subject><subject>Waist-Hip Ratio</subject><issn>0954-6820</issn><issn>1365-2796</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtuEzEUQC0EoqHwC8gbxGoG2zP22CyQUESgKKgSjwUr68aPdsJknNqZtmHFJ_CNfAl2E5Ut3vjq3nMfOghhSmqa36t1TRvBK9YpUTNCVE0YbWV9-wDN7gsP0Ywo3lZCMnKCnqS0JoQ2RJDH6ISqjreS8xn6uQjDEG7-_Po9bRMOHu8uHZ5DtH24hmSmASL-3KcfuB_x9zCNF3jRj2PCX3aT3ZdkXk8xjLYE3Wu8dNduSHcJkYfuXe43lzBeuFToWEZ5MLsQ01P0yMOQ3LPjf4q-Ld59nX-olufvz-Zvl5VpWyUraJgnq1YY3lphZCe4VYJJ5z1vHBhJO2WcscDFyjDGPaEAHhTYzoIXCppT9PIwdxvD1eTSTm_6ZNwwwOjClHTXNEy1lLaZlAfSxJBSdF5vY7-BuNeU6CJer3Xxq4tfXcTrO_H6Nrc-Py6ZVhtn_zUeTWfgxRHIWmHwEUbTp3suX94QJlXm3hy4m35w-_8-QH88P_tUwuYvuvGgSw</recordid><startdate>201004</startdate><enddate>201004</enddate><creator>Raiko, J. R. H.</creator><creator>Viikari, J. S. A.</creator><creator>Ilmanen, A.</creator><creator>Hutri‐Kähönen, N.</creator><creator>Taittonen, L.</creator><creator>Jokinen, E.</creator><creator>Pietikäinen, M.</creator><creator>Jula, A.</creator><creator>Loo, B.‐M.</creator><creator>Marniemi, J.</creator><creator>Lehtimäki, T.</creator><creator>Kähönen, M.</creator><creator>Rönnemaa, T.</creator><creator>Raitakari, O. T.</creator><creator>Juonala, M.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201004</creationdate><title>Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors</title><author>Raiko, J. R. H. ; Viikari, J. S. A. ; Ilmanen, A. ; Hutri‐Kähönen, N. ; Taittonen, L. ; Jokinen, E. ; Pietikäinen, M. ; Jula, A. ; Loo, B.‐M. ; Marniemi, J. ; Lehtimäki, T. ; Kähönen, M. ; Rönnemaa, T. ; Raitakari, O. 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Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Risk Factors</topic><topic>Waist-Hip Ratio</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Raiko, J. R. H.</creatorcontrib><creatorcontrib>Viikari, J. S. A.</creatorcontrib><creatorcontrib>Ilmanen, A.</creatorcontrib><creatorcontrib>Hutri‐Kähönen, N.</creatorcontrib><creatorcontrib>Taittonen, L.</creatorcontrib><creatorcontrib>Jokinen, E.</creatorcontrib><creatorcontrib>Pietikäinen, M.</creatorcontrib><creatorcontrib>Jula, A.</creatorcontrib><creatorcontrib>Loo, B.‐M.</creatorcontrib><creatorcontrib>Marniemi, J.</creatorcontrib><creatorcontrib>Lehtimäki, T.</creatorcontrib><creatorcontrib>Kähönen, M.</creatorcontrib><creatorcontrib>Rönnemaa, T.</creatorcontrib><creatorcontrib>Raitakari, O. T.</creatorcontrib><creatorcontrib>Juonala, M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of internal medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Raiko, J. R. H.</au><au>Viikari, J. S. A.</au><au>Ilmanen, A.</au><au>Hutri‐Kähönen, N.</au><au>Taittonen, L.</au><au>Jokinen, E.</au><au>Pietikäinen, M.</au><au>Jula, A.</au><au>Loo, B.‐M.</au><au>Marniemi, J.</au><au>Lehtimäki, T.</au><au>Kähönen, M.</au><au>Rönnemaa, T.</au><au>Raitakari, O. T.</au><au>Juonala, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors</atitle><jtitle>Journal of internal medicine</jtitle><addtitle>J Intern Med</addtitle><date>2010-04</date><risdate>2010</risdate><volume>267</volume><issue>4</issue><spage>370</spage><epage>384</epage><pages>370-384</pages><issn>0954-6820</issn><eissn>1365-2796</eissn><abstract>.  Raiko JRH, Viikari JSA, Ilmanen A, Hutri‐Kähönen N, Taittonen L, Jokinen E, Pietikäinen M, Jula A, Loo B.‐M, Marniemi J, Lehtimäki T, Kähönen M, Rönnemaa T, Raitakari OT, Juonala M (University of Turku; University of Tampere and Tampere University Hospital, Tampere; University of Oulu, Oulu; Vaasa Central Hospital, Vaasa; University of Helsinki, Helsinki; and Center of Social and Health Services, Kuopio; Finland). Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors. J Intern Med 2010; 267: 370–384. Objectives.  To examine cardiovascular risk factor levels in 2007 and their 6‐year changes between 2001 and 2007 using the data collected in the follow‐ups of the Cardiovascular Risk in Young Finns Study. Design.  Population‐based follow‐up study. Subjects.  A total of 2204 healthy Finnish adults aged 30–45 years (1210 women; 994 men). Main outcome measures.  Levels in 2007 and changes between 2001 and 2007 of lipids, insulin, glucose, blood pressure, smoking, body mass index, alcohol consumption, waist and hip circumferences. Results.  The mean serum total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol and triglyceride concentrations in 30‐ to 45‐year‐old adults were 5.05, 3.09, 1.34 and 1.40 mmol L−1, respectively. Significant changes (P &lt; 0.05) between 2001 and 2007 in 30‐ to 39‐year‐old subjects included a decrease in total cholesterol (−6.6% in men, −5.8% in women), LDL‐cholesterol (−10.2% and −11.6%) and an increase in diastolic blood pressure (3.5% and 3.9%). Waist circumference (1.8% and 5.5%) and systolic blood pressure increased in 36–39 year olds (2.3% and 2.3%). HDL‐cholesterol increased in 30‐ to 33‐year‐old women (5.8%) Glucose levels increased in 30‐ to 39‐year‐old women (3.7%) and 36‐ to 39‐year‐old men (3.6%). Smoking prevalence decreased in 36‐ to 39‐year‐old men from 29.8% to 22.2%. Conclusions.  The 6‐year changes in total cholesterol, LDL‐cholesterol and HDL‐cholesterol in young Finns were favourable between 2001 and 2007. However, waist circumference, glucose and blood pressure levels increased. Therefore, continuous efforts are still needed in fighting against cardiovascular risk factors.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19754855</pmid><doi>10.1111/j.1365-2796.2009.02148.x</doi><tpages>15</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Alcohol Drinking
Biological and medical sciences
Blood Glucose
Blood Pressure - physiology
Body Mass Index
cardiovascular
Cardiovascular Diseases - blood
Cardiovascular Diseases - physiopathology
change
Epidemiology
Female
Finland
Follow-Up Studies
General aspects
Humans
Insulin - blood
Lipids - blood
Male
Medical sciences
Metabolic Syndrome - epidemiology
Middle Aged
Miscellaneous
Prevalence
Public health. Hygiene
Public health. Hygiene-occupational medicine
Risk Factors
Waist-Hip Ratio
title Follow‐ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6‐year changes in risk factors
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