Contribution of Cyclophilin A to the Regulation of Inflammatory Processes in Rheumatoid Arthritis

Introduction Previous studies show that cyclophilin A (CypA) acts as a strong chemotactic cytokine to neutrophils, eosinophils, and monocytes in rheumatoid arthritis (RA). Methods In this study, monocytes were stimulated by purified CypA and the production of matrix metalloproteinase (MMPs), the cel...

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Veröffentlicht in:	Journal of clinical immunology 2010-01, Vol.30 (1), p.24-33
Hauptverfasser:	Wang, Li, Wang, Cong-hua, Jia, Jun-feng, Ma, Xiao-kui, Li, Yu, Zhu, Hong-bin, Tang, Hao, Chen, Zhi-nan, Zhu, Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - pathology Arthritis, Rheumatoid - physiopathology Biomedical and Life Sciences Biomedicine Cell Growth Processes - drug effects Cell Line, Tumor Cyclophilin A - genetics Cyclophilin A - immunology Cyclophilin A - metabolism Cyclophilin A - pharmacology Cytokines - biosynthesis Cytokines - genetics Humans Immunology Infectious Diseases Inflammation Internal Medicine Male Matrix Metalloproteinase 2 - biosynthesis Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 2 - immunology Matrix Metalloproteinase 9 - biosynthesis Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - immunology Medical Microbiology Mice Mice, SCID Monocytes - drug effects Monocytes - immunology Monocytes - metabolism Monocytes - pathology
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