Effector functions of human decidual NK cells in healthy early pregnancy are dependent on the specific engagement of natural cytotoxicity receptors

Abstract Natural killer (NK) cells represent the major lymphocyte population in the decidua basalis of the human uterus during healthy early pregnancy. The activity of decidual NK (dNK) cells and their activation status are different from those of peripheral blood (PB)-NK cells; i.e. dNK cells exhib...

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Veröffentlicht in:	Journal of reproductive immunology 2009-11, Vol.82 (2), p.142-147
Hauptverfasser:	El Costa, Hicham, Tabiasco, Julie, Berrebi, Alain, Parant, Olivier, Aguerre-Girr, Maryse, Piccinni, Marie-Pierre, Le Bouteiller, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Antigens, CD - biosynthesis Biological and medical sciences Cells, Cultured Chemokines Cytokines Cytotoxicity Cytotoxicity, Immunologic - immunology Decidua Decidua - pathology Embryology: invertebrates and vertebrates. Teratology Feedback, Physiological Female Fundamental and applied biological sciences. Psychology Humans Infection Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Killer Cells, Natural - pathology Lymphocytes Natural killer cells NCR NK Cell Lectin-Like Receptor Subfamily C - immunology NK Cell Lectin-Like Receptor Subfamily C - metabolism NKG2 antigen Obstetrics and Gynecology Peripheral blood Pregnancy Receptors, Natural Cytotoxicity Triggering - chemistry Receptors, Natural Cytotoxicity Triggering - immunology Receptors, Natural Cytotoxicity Triggering - metabolism Trophoblast Trophoblasts Uterus
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