Cardiopulmonary performance following changes in position and the administration of intravenous diazemuls
Twenty healthy volunteers entered a study to assess cardiopulmonary responses, as measured by pulse oximetry, following changes in posture in the dental chair and the administration of Diazemuls (diazepam) in doses sufficient to instill sedation (up to a maximum dose of 20 mg) in the volunteers to a...
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Veröffentlicht in: | Journal of dentistry 1992-08, Vol.20 (4), p.211-214 |
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creator | Gallon, P. Walton, G.M. Rood, J.P. |
description | Twenty healthy volunteers entered a study to assess cardiopulmonary responses, as measured by pulse oximetry, following changes in posture in the dental chair and the administration of Diazemuls (diazepam) in doses sufficient to instill sedation (up to a maximum dose of 20 mg) in the volunteers to a degree such that ptosis was seen. The results indicate that
SaO
2 values remained above 95 per cent throughout the study. It is concluded that although changes in
SaO
2 and pulse rate do occur, these differences are not important in healthy individuals, although they may be more serious in patients with pre-existing cardiopulmonary disease. |
doi_str_mv | 10.1016/0300-5712(92)90080-V |
format | Article |
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SaO
2 values remained above 95 per cent throughout the study. It is concluded that although changes in
SaO
2 and pulse rate do occur, these differences are not important in healthy individuals, although they may be more serious in patients with pre-existing cardiopulmonary disease.</description><identifier>ISSN: 0300-5712</identifier><identifier>EISSN: 1879-176X</identifier><identifier>DOI: 10.1016/0300-5712(92)90080-V</identifier><identifier>PMID: 1430510</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Anesthesia, Intravenous ; Anesthesia, Local ; Conscious Sedation ; Dentistry ; Diazepam - administration & dosage ; Female ; Humans ; Male ; Oximetry ; Oxygen - blood ; Oxygen Consumption - drug effects ; Pharmacology ; Physiology ; Posture ; Pulse - drug effects ; Sedation ; Supine Position ; Time Factors</subject><ispartof>Journal of dentistry, 1992-08, Vol.20 (4), p.211-214</ispartof><rights>1992</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c306t-f639acec42a1003ce969817ee131168e3e56f8725a7d4db1bd30c012d978ed2e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0300-5712(92)90080-V$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1430510$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gallon, P.</creatorcontrib><creatorcontrib>Walton, G.M.</creatorcontrib><creatorcontrib>Rood, J.P.</creatorcontrib><title>Cardiopulmonary performance following changes in position and the administration of intravenous diazemuls</title><title>Journal of dentistry</title><addtitle>J Dent</addtitle><description>Twenty healthy volunteers entered a study to assess cardiopulmonary responses, as measured by pulse oximetry, following changes in posture in the dental chair and the administration of Diazemuls (diazepam) in doses sufficient to instill sedation (up to a maximum dose of 20 mg) in the volunteers to a degree such that ptosis was seen. The results indicate that
SaO
2 values remained above 95 per cent throughout the study. It is concluded that although changes in
SaO
2 and pulse rate do occur, these differences are not important in healthy individuals, although they may be more serious in patients with pre-existing cardiopulmonary disease.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anesthesia, Intravenous</subject><subject>Anesthesia, Local</subject><subject>Conscious Sedation</subject><subject>Dentistry</subject><subject>Diazepam - administration & dosage</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Oximetry</subject><subject>Oxygen - blood</subject><subject>Oxygen Consumption - drug effects</subject><subject>Pharmacology</subject><subject>Physiology</subject><subject>Posture</subject><subject>Pulse - drug effects</subject><subject>Sedation</subject><subject>Supine Position</subject><subject>Time Factors</subject><issn>0300-5712</issn><issn>1879-176X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVpSLdp_0EKOpX04HTG8srWpRCWfBQCvaShN6GVxomCLbmSndD8-mq7ob0VBoaZeefrYewY4RQB5WcQANW6xfpE1Z8UQAfV7Su2wq5VFbbyx2u2-it5w97m_AAADdTqkB1iI2CNsGJ-Y5LzcVqGMQaTfvGJUh_TaIIl3sdhiE8-3HF7b8IdZe4Dn2L2s4-Bm-D4fE_cuNEHn-dk_qRjX1QleKQQl8ydN880LkN-xw56M2R6_-KP2PeL85vNVXX97fLr5uy6sgLkXPVSKGPJNrVBAGFJSdVhS4QCUXYkaC37rq3XpnWN2-LWCbCAtVNtR64mccQ-7udOKf5cKM969NnSMJhA5SDdClHLRmIRNnuhTTHnRL2ekh8LA42gd4T1Dp_e4dOq2I6wvi1tH17mL9uR3L-mPdJS_7KvU3ny0VPS2XoqOJ1PZGftov__gt80hI06</recordid><startdate>19920801</startdate><enddate>19920801</enddate><creator>Gallon, P.</creator><creator>Walton, G.M.</creator><creator>Rood, J.P.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920801</creationdate><title>Cardiopulmonary performance following changes in position and the administration of intravenous diazemuls</title><author>Gallon, P. ; Walton, G.M. ; Rood, J.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c306t-f639acec42a1003ce969817ee131168e3e56f8725a7d4db1bd30c012d978ed2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anesthesia, Intravenous</topic><topic>Anesthesia, Local</topic><topic>Conscious Sedation</topic><topic>Dentistry</topic><topic>Diazepam - administration & dosage</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Oximetry</topic><topic>Oxygen - blood</topic><topic>Oxygen Consumption - drug effects</topic><topic>Pharmacology</topic><topic>Physiology</topic><topic>Posture</topic><topic>Pulse - drug effects</topic><topic>Sedation</topic><topic>Supine Position</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gallon, P.</creatorcontrib><creatorcontrib>Walton, G.M.</creatorcontrib><creatorcontrib>Rood, J.P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gallon, P.</au><au>Walton, G.M.</au><au>Rood, J.P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiopulmonary performance following changes in position and the administration of intravenous diazemuls</atitle><jtitle>Journal of dentistry</jtitle><addtitle>J Dent</addtitle><date>1992-08-01</date><risdate>1992</risdate><volume>20</volume><issue>4</issue><spage>211</spage><epage>214</epage><pages>211-214</pages><issn>0300-5712</issn><eissn>1879-176X</eissn><abstract>Twenty healthy volunteers entered a study to assess cardiopulmonary responses, as measured by pulse oximetry, following changes in posture in the dental chair and the administration of Diazemuls (diazepam) in doses sufficient to instill sedation (up to a maximum dose of 20 mg) in the volunteers to a degree such that ptosis was seen. The results indicate that
SaO
2 values remained above 95 per cent throughout the study. It is concluded that although changes in
SaO
2 and pulse rate do occur, these differences are not important in healthy individuals, although they may be more serious in patients with pre-existing cardiopulmonary disease.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>1430510</pmid><doi>10.1016/0300-5712(92)90080-V</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Adolescent Adult Anesthesia, Intravenous Anesthesia, Local Conscious Sedation Dentistry Diazepam - administration & dosage Female Humans Male Oximetry Oxygen - blood Oxygen Consumption - drug effects Pharmacology Physiology Posture Pulse - drug effects Sedation Supine Position Time Factors |
title | Cardiopulmonary performance following changes in position and the administration of intravenous diazemuls |
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