Synthesis and Structure-activity Relationship of Antifungal Coniothyriomycin Analogues

The structure of the antifungal metabolite coniothyriomycin was systematically modified by changing the acids of the open chain imide, modification of the hydrophobicity, variation in the degree of saturation, replacement of carbons by nitrogen or oxygen, and incorporation of the open chain molecule...

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Veröffentlicht in:	Journal of antibiotics 2003/03/25, Vol.56(3), pp.296-305
Hauptverfasser:	KROHN, KARSTEN, ELSÄSSER, BRIGITTA, ANTUS, SÁNDOR, KÓNYA, KRISZTINA, AMMERMANN, EBERHARD
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - chemical synthesis Antifungal Agents - chemistry Antifungal Agents - pharmacology Biological and medical sciences Imides - chemical synthesis Imides - chemistry Imides - pharmacology Magnetic Resonance Spectroscopy Medical sciences Molecular Structure Structure-Activity Relationship
Online-Zugang:	Volltext
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