The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

The secretory factor VEGF-C has been directly implicated in various physiological processes during embryogenesis and human cancers. However, the importance of the conversion of its precursor proVEGF-C to mature VEGF-C in tumorigenesis, and vessel formation and the identity of the protease(s) that re...

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Veröffentlicht in:	The Journal of clinical investigation 2003-06, Vol.111 (11), p.1723
Hauptverfasser:	Siegfried, Geraldine, Basak, Ajoy, Cromlish, James A, Benjannet, Suzanne, Marcinkiewicz, Jadwiga, Chrétien, Michel, Seidah, Nabil G, Khatib, Abdel-Majid
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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