Synthesis of 3-substituted indoles via reactive alkylideneindolenine intermediates

Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the pre...

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Veröffentlicht in:Organic & biomolecular chemistry 2010-03, Vol.8 (6), p.1259-1270
Hauptverfasser: Palmieri, Alessandro, Petrini, Marino, Shaikh, Rafik R
Format: Artikel
Sprache:eng
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Zusammenfassung:Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the preparation of functionalized indole derivatives.
ISSN:1477-0520
1477-0539
DOI:10.1039/b919891a