Synthesis of 3-substituted indoles via reactive alkylideneindolenine intermediates
Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the pre...
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Veröffentlicht in: | Organic & biomolecular chemistry 2010-03, Vol.8 (6), p.1259-1270 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Elimination of suitable leaving groups from 3-substituted indoles under basic or acidic conditions readily provides alkylideneindolenine intermediates that may react with a large variety of nucleophilic reagents. This article highlights some recent developments of this synthetic approach for the preparation of functionalized indole derivatives. |
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ISSN: | 1477-0520 1477-0539 |
DOI: | 10.1039/b919891a |