QDs-DNA nanosensor for the detection of hepatitis B virus DNA and the single-base mutants

We report here a quantum dots-DNA (QDs-DNA) nanosensor based on fluorescence resonance energy transfer (FRET) for the detection of the target DNA and single mismatch in hepatitis B virus (HBV) gene. The proposed one-pot DNA detection method is simple, rapid and efficient due to the elimination of th...

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Veröffentlicht in:	Biosensors & bioelectronics 2010-04, Vol.25 (8), p.1934-1940
Hauptverfasser:	Wang, Xiang, Lou, Xinhui, Wang, Yi, Guo, Qingchuan, Fang, Zheng, Zhong, Xinhua, Mao, Hongju, Jin, Qinghui, Wu, Lei, Zhao, Hui, Zhao, Jianlong
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biosensing Techniques - instrumentation Biotechnology DNA DNA Mutational Analysis - instrumentation DNA, Viral - analysis DNA, Viral - genetics Equipment Design Equipment Failure Analysis Fluorescence resonance energy transfer (FRET) Fluorescence Resonance Energy Transfer - instrumentation Fundamental and applied biological sciences. Psychology Hepatitis B virus (HBV) Hepatitis B virus - genetics Mutation Nanotechnology - instrumentation Oligonucleotide Array Sequence Analysis - instrumentation Quantum Dots Quantum dots (QDs) Reproducibility of Results Sensitivity and Specificity
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