Improvements in cheek volume in lipoatrophic individuals switching away from thymidine nucleoside reverse transcriptase inhibitors

Background Thymidine nucleoside reverse transcriptase inhibitors (NRTIs) are associated with subcutaneous fat loss. Facial changes cannot be assessed by dual‐energy X‐ray absorptiometry (DEXA) scans. There are limited objective data on the reversibility of facial lipoatrophy. Methods We performed a...

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Veröffentlicht in:	HIV medicine 2009-07, Vol.10 (6), p.351-355
Hauptverfasser:	Benn, P, Sauret‐Jackson, V, Cartledge, J, Ruff, C, Sabin, CA, Moyle, G, Linney, A, Reilly, G, Edwards, SG
Format:	Artikel
Sprache:	eng
Schlagworte:	3D surface laser scans abacavir Absorptiometry, Photon Adenine - analogs & derivatives Adenine - therapeutic use Adult Aged Body Composition - drug effects Body Composition - physiology Cheek - pathology Dideoxynucleosides - therapeutic use facial lipoatrophy Female HIV HIV Infections - complications HIV Infections - drug therapy HIV-1 HIV-Associated Lipodystrophy Syndrome - chemically induced HIV-Associated Lipodystrophy Syndrome - drug therapy HIV-Associated Lipodystrophy Syndrome - pathology Human immunodeficiency virus Humans lipodystrophy Male Middle Aged Organophosphonates - therapeutic use Quality of Life Reverse Transcriptase Inhibitors - adverse effects stavudine Stavudine - therapeutic use Tenofovir tenofovir DF zidovudine Zidovudine - therapeutic use
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