Synthesis and Antiviral Evaluation of 4'-alkoxy Analogues of 9-(β-D-xylofuranosyl)adenine

Background: Motivated by the reported biological activity of 9-(β-D-xylofuranosyl)adenine (xylo-A), the synthesis of its 4'-alkoxy analogues was carried out. Methods: The starting material 9-(3-deoxy-β-D-glycero-pento–3-enofuranosyl)adenine (1) was prepared from adenosine. Compound 1 was conver...

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Veröffentlicht in:Antiviral chemistry & chemotherapy 2009-04, Vol.19 (5), p.201-212
Hauptverfasser: Kubota, Yutaka, Ishizaki, Nobuhide, Kaneda, Yuri, Haraguchi, Kazuhiro, Odanaka, Yuki, Tanaka, Hiromichi, Kato, Nobuyuki, Baba, Masanori, Balzarini, Jan
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