Dofetilide, A Novel Class III Antiarrhythmic Agent

Dofetilide is a potent and selective class III antiarrhythmic agent that is under development for the treatment of re-entrant tachyarrhythmias (ventricular tachycardia/ventricular fibrillation, atrial fibrillation/ atrial flutter, and paraoxysmal supraventricular tachycardia). In animal studies, dof...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1992-12, Vol.20 (3 Suppl), p.96-105
Hauptverfasser:	Rasmussen, H S, Allen, M J, Blackburn, K J, Butrous, G S, Dalrymple, H W
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Animals Anti-Arrhythmia Agents - therapeutic use Antiarythmic agents Arrhythmias, Cardiac - drug therapy Biological and medical sciences Cardiovascular system Electrocardiography - drug effects Electrophysiology Heart - physiology Humans Medical sciences Pharmacology. Drug treatments Phenethylamines - metabolism Phenethylamines - pharmacokinetics Phenethylamines - therapeutic use Sulfonamides - metabolism Sulfonamides - pharmacokinetics Sulfonamides - therapeutic use
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