Identification of a neuropeptide hormone that regulates sex pheromone production in female moths

A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino ac...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1989-05, Vol.244 (4906), p.796-798
Hauptverfasser: Raina, A.K. (USDA, ARS, Insect Chemical Ecology Laboratory, Beltsville, MD.), Jaffe, H, Kempe, T.G, Keim, P, Blacher, R.W, Fales, H.M, Riley, C.T, Klun, J.A, Ridgway, R.L, Hayes, D.K
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container_issue 4906
container_start_page 796
container_title Science (American Association for the Advancement of Science)
container_volume 244
creator Raina, A.K. (USDA, ARS, Insect Chemical Ecology Laboratory, Beltsville, MD.)
Jaffe, H
Kempe, T.G
Keim, P
Blacher, R.W
Fales, H.M
Riley, C.T
Klun, J.A
Ridgway, R.L
Hayes, D.K
description A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino acid sequence has no significant homology with any of the fully characterized peptide hormones. The synthetic peptide, at a dose of between 2 and 4 picomoles, induced production of a normal quantity of sex pheromone in ligated H. zea females. The peptide also induced pheromone production in six other species of moths, thus indicating that this or similar peptides may be responsible for the regulation of pheromone production in moths
doi_str_mv 10.1126/science.244.4906.796
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(USDA, ARS, Insect Chemical Ecology Laboratory, Beltsville, MD.) ; Jaffe, H ; Kempe, T.G ; Keim, P ; Blacher, R.W ; Fales, H.M ; Riley, C.T ; Klun, J.A ; Ridgway, R.L ; Hayes, D.K</creator><creatorcontrib>Raina, A.K. (USDA, ARS, Insect Chemical Ecology Laboratory, Beltsville, MD.) ; Jaffe, H ; Kempe, T.G ; Keim, P ; Blacher, R.W ; Fales, H.M ; Riley, C.T ; Klun, J.A ; Ridgway, R.L ; Hayes, D.K</creatorcontrib><description>A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino acid sequence has no significant homology with any of the fully characterized peptide hormones. The synthetic peptide, at a dose of between 2 and 4 picomoles, induced production of a normal quantity of sex pheromone in ligated H. zea females. 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Psychology ; Ganglia ; HELICOVERPA ZEA ; Heliothis zea ; HEMBRA ; HORMONAS ; HORMONAS DE INVERTEBRADOS ; HORMONE ; HORMONE D'INVERTEBRE ; Hormones ; LEPIDOPTERA ; Moths ; Neuropeptides ; Noctuidae ; PEPTIDE ; Peptide hormones ; PEPTIDOS ; PHEROMONE ; Pheromones ; Physiological aspects ; Proteins ; Sex attractants ; SEXE ; SEXO ; SISTEMA NERVIOSO ; Sulfoxides ; SYSTEME NERVEUX</subject><ispartof>Science (American Association for the Advancement of Science), 1989-05, Vol.244 (4906), p.796-798</ispartof><rights>Copyright 1989 The American Association for the Advancement of Science</rights><rights>1991 INIST-CNRS</rights><rights>COPYRIGHT 1989 American Association for the Advancement of Science</rights><rights>COPYRIGHT 1989 American Association for the Advancement of Science</rights><rights>Copyright American Association for the Advancement of Science May 19, 1989</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c761t-f3cf3e58bb3fe263ddbd16f9d84cbdff39fbe5634109320763df71e7c1684f2c3</citedby><cites>FETCH-LOGICAL-c761t-f3cf3e58bb3fe263ddbd16f9d84cbdff39fbe5634109320763df71e7c1684f2c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1703518$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1703518$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,2871,2872,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=19409071$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17802237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Raina, A.K. (USDA, ARS, Insect Chemical Ecology Laboratory, Beltsville, MD.)</creatorcontrib><creatorcontrib>Jaffe, H</creatorcontrib><creatorcontrib>Kempe, T.G</creatorcontrib><creatorcontrib>Keim, P</creatorcontrib><creatorcontrib>Blacher, R.W</creatorcontrib><creatorcontrib>Fales, H.M</creatorcontrib><creatorcontrib>Riley, C.T</creatorcontrib><creatorcontrib>Klun, J.A</creatorcontrib><creatorcontrib>Ridgway, R.L</creatorcontrib><creatorcontrib>Hayes, D.K</creatorcontrib><title>Identification of a neuropeptide hormone that regulates sex pheromone production in female moths</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino acid sequence has no significant homology with any of the fully characterized peptide hormones. The synthetic peptide, at a dose of between 2 and 4 picomoles, induced production of a normal quantity of sex pheromone in ligated H. zea females. The peptide also induced pheromone production in six other species of moths, thus indicating that this or similar peptides may be responsible for the regulation of pheromone production in moths</description><subject>Amides</subject><subject>Amino acids</subject><subject>Aminoacids, peptides. Hormones. 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Psychology</topic><topic>Ganglia</topic><topic>HELICOVERPA ZEA</topic><topic>Heliothis zea</topic><topic>HEMBRA</topic><topic>HORMONAS</topic><topic>HORMONAS DE INVERTEBRADOS</topic><topic>HORMONE</topic><topic>HORMONE D'INVERTEBRE</topic><topic>Hormones</topic><topic>LEPIDOPTERA</topic><topic>Moths</topic><topic>Neuropeptides</topic><topic>Noctuidae</topic><topic>PEPTIDE</topic><topic>Peptide hormones</topic><topic>PEPTIDOS</topic><topic>PHEROMONE</topic><topic>Pheromones</topic><topic>Physiological aspects</topic><topic>Proteins</topic><topic>Sex attractants</topic><topic>SEXE</topic><topic>SEXO</topic><topic>SISTEMA NERVIOSO</topic><topic>Sulfoxides</topic><topic>SYSTEME NERVEUX</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Raina, A.K. 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(USDA, ARS, Insect Chemical Ecology Laboratory, Beltsville, MD.)</au><au>Jaffe, H</au><au>Kempe, T.G</au><au>Keim, P</au><au>Blacher, R.W</au><au>Fales, H.M</au><au>Riley, C.T</au><au>Klun, J.A</au><au>Ridgway, R.L</au><au>Hayes, D.K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of a neuropeptide hormone that regulates sex pheromone production in female moths</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1989-05-19</date><risdate>1989</risdate><volume>244</volume><issue>4906</issue><spage>796</spage><epage>798</epage><pages>796-798</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><coden>SCIEAS</coden><abstract>A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino acid sequence has no significant homology with any of the fully characterized peptide hormones. The synthetic peptide, at a dose of between 2 and 4 picomoles, induced production of a normal quantity of sex pheromone in ligated H. zea females. The peptide also induced pheromone production in six other species of moths, thus indicating that this or similar peptides may be responsible for the regulation of pheromone production in moths</abstract><cop>Washington, DC</cop><pub>The American Association for the Advancement of Science</pub><pmid>17802237</pmid><doi>10.1126/science.244.4906.796</doi><tpages>3</tpages></addata></record>
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source American Association for the Advancement of Science; Jstor Complete Legacy
subjects Amides
Amino acids
Aminoacids, peptides. Hormones. Neuropeptides
Analysis
Analytical, structural and metabolic biochemistry
Biochemistry
Biological and medical sciences
BIOSINTESIS
BIOSYNTHESE
Biosynthesis
Butterflies & moths
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
Female animals
FEMELLE
FEROMONAS
Fundamental and applied biological sciences. Psychology
Ganglia
HELICOVERPA ZEA
Heliothis zea
HEMBRA
HORMONAS
HORMONAS DE INVERTEBRADOS
HORMONE
HORMONE D'INVERTEBRE
Hormones
LEPIDOPTERA
Moths
Neuropeptides
Noctuidae
PEPTIDE
Peptide hormones
PEPTIDOS
PHEROMONE
Pheromones
Physiological aspects
Proteins
Sex attractants
SEXE
SEXO
SISTEMA NERVIOSO
Sulfoxides
SYSTEME NERVEUX
title Identification of a neuropeptide hormone that regulates sex pheromone production in female moths
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T00%3A27%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Identification%20of%20a%20neuropeptide%20hormone%20that%20regulates%20sex%20pheromone%20production%20in%20female%20moths&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Raina,%20A.K.%20(USDA,%20ARS,%20Insect%20Chemical%20Ecology%20Laboratory,%20Beltsville,%20MD.)&rft.date=1989-05-19&rft.volume=244&rft.issue=4906&rft.spage=796&rft.epage=798&rft.pages=796-798&rft.issn=0036-8075&rft.eissn=1095-9203&rft.coden=SCIEAS&rft_id=info:doi/10.1126/science.244.4906.796&rft_dat=%3Cgale_proqu%3EA7652303%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=213539952&rft_id=info:pmid/17802237&rft_galeid=A7652303&rft_jstor_id=1703518&rfr_iscdi=true