Prognostic significance of tumor oxygenation in humans

Low tissue oxygen concentration has been shown to be important in the response of human tumors to radiation therapy, chemotherapy and other treatment modalities. Hypoxia is also known to be a prognostic indicator, as hypoxic human tumors are more biologically aggressive and are more likely to recur...

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Veröffentlicht in:	Cancer letters 2003-05, Vol.195 (1), p.1-16
Hauptverfasser:	Evans, Sydney M., Koch, Cameron J.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Nitroimidazole Animals Biological and medical sciences Biomarkers - analysis CA9 Cancer Cancer therapies Case Management Cell Hypoxia Drug dosages EF5 Electrodes Energy Metabolism HIF1 Humans Hypoxia Measurement techniques Medical sciences Neoplasm Invasiveness Neoplasm Metastasis Neoplasms - metabolism Neoplasms - pathology Nitroimidazoles - analysis Oximetry - instrumentation Oximetry - methods Oxygen - analysis Oxygen Consumption Partial Pressure Patients PET imaging Polarographic needle electrodes Prognosis Radiation resistance Radiation therapy Radiopharmaceuticals - analysis Radiopharmaceuticals - pharmacokinetics Rodentia SPECT imaging Tomography, Emission-Computed Tumors Vascular endothelial growth factor
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