Somatostatin receptor scintigraphy in pediatric bronchial carcinoid tumor

Carcinoid tumor is a rare neuroendocrine neoplasm with different locations, the most frequent ones during the pediatric age being the appendix and lung. Scintigraphy with (111)In-DTPA-d-Phe(1)-octreotide has led to an importance advance in the diagnosis of extension in carcinoid tumor patients. We p...

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Veröffentlicht in:Revista española de medicina nuclear 2010-01, Vol.29 (1), p.25-28
Hauptverfasser: Hervás Benito, I, Bello Arques, P, Loaiza, J L, Vercher, J L, Velasco, R P, Rivas Sánchez, A, Ruiz Llorca, C, Martí Vidal, J F, Mateo Navarro, A
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container_title Revista española de medicina nuclear
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creator Hervás Benito, I
Bello Arques, P
Loaiza, J L
Vercher, J L
Velasco, R P
Rivas Sánchez, A
Ruiz Llorca, C
Martí Vidal, J F
Mateo Navarro, A
description Carcinoid tumor is a rare neuroendocrine neoplasm with different locations, the most frequent ones during the pediatric age being the appendix and lung. Scintigraphy with (111)In-DTPA-d-Phe(1)-octreotide has led to an importance advance in the diagnosis of extension in carcinoid tumor patients. We present three pediatric patients with bronchial carcinoid studied with somatostatin analogue scintigraphy (SSRS). The first patient (9 years) was studied using the SSRS after surgery due to carcinoid tumor in the right lower lobe in which tumor remains was observed (this being clearer in the tomography study). The second patient (10 years) presented due to endobronchial tumor in the left lower lobe together with atelectasis of the LUL and emphysema of the LLL. Radiology imaging techniques suggested the differential diagnosis between the endobronchial carcinoid tumor or plasma cells or foreign body gramuloma. The SSRS showed an abnormal deposit of activity in the left hemithorax consisted with carcinoid tumor. No other areas suggesting metastasis were observed. After the surgery (endobronchial resection), new controls with SSRS showed absence of disease. The third patient (12 years) came after a lobectomy (RUL) due to bronchial carcinoid. The SSRS did not show any abnormal areas of activity. In the subsequent control (3 months), a deposit of activity was observed in the middle third of the right hemithorax, after which a lobectomy was performed (RLL and ML) that showed small remains of neuroendocrine carcinoid. Subsequent controls were negative. The SSRS has demonstrated great utility in the diagnosis, follow-up and staging of pediatric patients, carriers of neuroendocrine carcinoid tumors.
doi_str_mv 10.1016/j.remn.2009.03.003
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subjects Biomarkers, Tumor - analysis
Bronchial Neoplasms - chemistry
Bronchial Neoplasms - diagnostic imaging
Bronchial Neoplasms - surgery
Carcinoid Tumor - chemistry
Carcinoid Tumor - diagnostic imaging
Carcinoid Tumor - surgery
Child
Diagnosis, Differential
Female
Humans
Indium Radioisotopes
Lung Neoplasms - chemistry
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - surgery
Male
Neoplasm Proteins - analysis
Octreotide - analogs & derivatives
Pneumonectomy
Postoperative Care
Postoperative Complications - etiology
Pulmonary Atelectasis - etiology
Pulmonary Emphysema - etiology
Radionuclide Imaging
Radiopharmaceuticals
Receptors, Somatostatin - analysis
Reoperation
title Somatostatin receptor scintigraphy in pediatric bronchial carcinoid tumor
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