Modulation of constitutive and delayed apoptosis by brefeldin A in human neutrophils

Neutrophil apoptosis is a constitutive process that can be enhanced or delayed by various stimuli. In this study, the effect of brefeldin A (BFA), which affects the biological process of secretion, on constitutive and delayed apoptosis of neutrophils was investigated. Neutrophil apoptosis was determ...

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Veröffentlicht in:	International immunopharmacology 2003-06, Vol.3 (6), p.835-843
Hauptverfasser:	Lee, Min-Jung, Park, Ji-Yeon, Lee, Sun-Young, Lee, Jun-Sik, Jung, Dong-Keun, Bae, Yoe-Sik, Kwak, Jong-Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis Apoptosis - drug effects Biological and medical sciences Blotting, Western Brefeldin A Brefeldin A - pharmacology Caspase Caspase 3 Caspase Inhibitors DNA Fragmentation - drug effects Dose-Response Relationship, Drug Humans Immunomodulators In Vitro Techniques Indicators and Reagents Mcl-1 Medical sciences Neutrophils Neutrophils - drug effects Pharmacology. Drug treatments Phosphatidylinositols - pharmacology Phosphatidylserines - pharmacology Protein Kinase C - antagonists & inhibitors Protein Kinase C-delta Protein kinase C-δ Protein Synthesis Inhibitors - pharmacology
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