CRAC channels: activation, permeation, and the search for a molecular identity

The Ca 2+ release-activated Ca 2+ (CRAC) channel is a highly Ca 2+-selective store-operated channel that is expressed in T lymphocytes, mast cells, and other hematopoietic cells. In T cells, CRAC channels are essential for generating the prolonged intracellular Ca 2+ ([Ca 2+] i) elevation required f...

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Veröffentlicht in:Cell calcium (Edinburgh) 2003-05, Vol.33 (5), p.311-321
Hauptverfasser: Prakriya, Murali, Lewis, Richard S.
Format: Artikel
Sprache:eng
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