Improvement of cardiac function and remodeling by transplanting adipose tissue-derived stromal cells into a mouse model of acute myocardial infarction

Abstract Background We investigated the effect of adipose tissue-derived stromal cells (ADSC) therapy on cardiac contractility and remodeling in the C57BL/6 mouse model of acute myocardial infarction (AMI). Methods 30 adult male C57BL/6 mice were randomized into 2 groups, namely, AMI + media (contro...

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Veröffentlicht in:	International journal of cardiology 2010-03, Vol.139 (2), p.166-172
Hauptverfasser:	Yu, Long Hao, Kim, Moo Hyun, Park, Tae Ho, Cha, Kwang Soo, Kim, Young Dae, Quan, Mei Lian, Rho, Mi Sook, Seo, Su Yeoung, Jung, Jin Sup
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adipose Tissue, Brown - cytology Animals Biological and medical sciences Biomarkers - metabolism Cardiology. Vascular system Cardiovascular Cell Transplantation - methods Cicatrix - pathology Coronary heart disease Disease Models, Animal Echocardiography Heart Heart Function Tests Immunohistochemistry Lymphokines Male Medical sciences Mice Mice, Inbred C57BL Myocardial Contraction - physiology Myocardial infarction Myocardial Infarction - diagnostic imaging Myocardial Infarction - pathology Myocardial Infarction - therapy Myocarditis. Cardiomyopathies Myocardium - pathology Stromal Cells - metabolism Stromal Cells - transplantation Transplantation Ventricular Remodeling - physiology
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