Oxidative stress and lipid peroxidation products:effect of pinealectomy or exogenous melatonin injections on biomarkers of tissue damage during acute pancreatitis

BACKGROUND:Melatonin (N-acetyl-5-methoxytripta-mine) is a free radical scavenger and a strong antioxidant,secreted by the pineal gland.In this study,we evaluated the effects of decreasing and increasing serum melatonin levels on malonyldialdehyde (MDA),superoxide dismutase (SOD),and reduced glutathi...

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Veröffentlicht in:	Hepatobiliary & pancreatic diseases international 2010-02, Vol.9 (1), p.78-82
Hauptverfasser:	Col, Cavit, Dinler, Kahraman, Hasdemir, Oguz, Buyukasik, Oktay, Bugdayci, Guler
Format:	Artikel
Sprache:	eng
Schlagworte:	acute Acute Disease Animals Antioxidants - administration & dosage Antioxidants - pharmacology Biomarkers - metabolism damage Disease Models, Animal gland Glutathione - metabolism Injections, Intramuscular Ligation Lipid Peroxidation - drug effects Male Malondialdehyde - metabolism melatonin Melatonin - administration & dosage Melatonin - pharmacology oxidative Oxidative Stress - drug effects Pancreas - metabolism pancreatitis Pancreatitis - etiology Pancreatitis - metabolism pineal Pineal Gland - metabolism Pineal Gland - surgery Rats Rats, Wistar Superoxide Dismutase - metabolism
Online-Zugang:	Volltext
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