Histopathological and cytological examination of autopsy cases with multiple organ dysfunction syndromes

To evaluate the role of small scavenger receptor A (SRA)‐positive (SRA+) cells and large SRA+ cells in the peripheral blood (PB) in the pathophysiological mechanisms underlying multiple organ dysfunction syndromes (MODS), 24 autopsy cases with MODS were examined. In addition to histopathological and...

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Veröffentlicht in:	Pathology international 2010-06, Vol.60 (6), p.443-451
Hauptverfasser:	Emura, Iwao, Usuda, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Autopsy Cell Count contraction band necrosis cytokine Cytokines - metabolism diffuse alveolar damage Female Humans Lung Injury - complications Lung Injury - metabolism Lung Injury - pathology Male Middle Aged Monocytes - metabolism Monocytes - pathology multiple organ dysfunction syndrome Multiple Organ Failure - complications Multiple Organ Failure - metabolism Multiple Organ Failure - pathology Myocytes, Cardiac - metabolism Myocytes, Cardiac - pathology Necrosis - metabolism Necrosis - pathology peripheral blood scavenger receptor-A positive cells Scavenger Receptors, Class A - metabolism
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Zusammenfassung:	To evaluate the role of small scavenger receptor A (SRA)‐positive (SRA+) cells and large SRA+ cells in the peripheral blood (PB) in the pathophysiological mechanisms underlying multiple organ dysfunction syndromes (MODS), 24 autopsy cases with MODS were examined. In addition to histopathological and immunohistochemical examination, cytokine levels of cardiac blood, the SRA index (number of small SRA+ cells in 10 high power fields, upper limit
ISSN:	1320-5463 1440-1827
DOI:	10.1111/j.1440-1827.2010.02539.x