Growth-associated glycosylation of transferrin secreted by HepG2 cells

Growth-associated alterations in the oligosaccharide structures of transferrin secreted by HepG2 cells were examined by concanavalin A-crossed affinoimmuno-electrophoresis. Slowly dividing, confluent cultures produced transferrin with a approximately 4.5-fold greater proportion of biantennary comple...

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Veröffentlicht in:	The Journal of biological chemistry 1992-11, Vol.267 (33), p.23982-23987
Hauptverfasser:	HAHN, T. J, GOOCHEE, C. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Carbohydrate Sequence Carcinoma, Hepatocellular Cell Division Clone Cells Fundamental and applied biological sciences. Psychology Galactosyltransferases - metabolism Glycoproteins Glycosylation HepG2 cells Humans isoforms Kinetics Liver Neoplasms man Molecular Sequence Data N-acetylglucosaminyltransferase V N-Acetylglucosaminyltransferases - metabolism Proteins requirements secretion Time Factors transferrin Transferrin - biosynthesis Transferrin - isolation & purification Transferrin - metabolism Tumor Cells, Cultured
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