Genetic and environmental determinants of total and high-molecular weight adiponectin in families with low HDL-cholesterol and early onset coronary heart disease

Abstract Objective Plasma adiponectin and high-density lipoprotein cholesterol (HDL-C) exhibit a well-known positive metabolic correlation. Neither heritability nor genome-wide linkage analysis for the high-molecular weight (HMW) adiponectin is available. This work estimates the genetic and environm...

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Veröffentlicht in:	Atherosclerosis 2010-06, Vol.210 (2), p.479-485
Hauptverfasser:	Kangas-Kontio, Tiia, Huotari, Anne, Ruotsalainen, Heli, Herzig, Karl-Heinz, Tamminen, Minna, Ala-Korpela, Mika, Savolainen, Markku J, Kakko, Sakari
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - genetics Adiponectin - metabolism Adult Age of Onset Atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Bivariate Blood and lymphatic vessels Blood. Blood coagulation. Reticuloendothelial system Cardiology. Vascular system Cardiovascular Cholesterol, HDL - metabolism Chromosome Mapping Coronary Disease - genetics Coronary Disease - metabolism Environment Family Health Female Finland Genome-Wide Association Study Humans Linkage Male Medical sciences Middle Aged Models, Genetic Molecular Weight Pharmacology. Drug treatments
Online-Zugang:	Volltext
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