Challenging Small Human Hepatocytes with Opiates: Further Characterization of a Novel Prototype Bioartificial Liver

Bioartificial liver (BAL) systems can take over liver functions in patients undergoing liver failure until transplantation. Recently, a novel prototype rotary BAL has been developed using small human hepatocytes (SH). This study investigated the metabolism of opiates morphine and methadone in the BA...

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Veröffentlicht in:	Tissue engineering. Part A 2010-03, Vol.16 (3), p.87-813
Hauptverfasser:	Wurm, Martin, Woess, Claudia, Libiseller, Kathrin, Beer, Beate, Pavlic, Marion
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Cell Count Cell culture Cell Culture Techniques Cell Extracts Cell Survival - drug effects Cells, Cultured Health aspects Hepatocytes - cytology Hepatocytes - drug effects Hepatocytes - metabolism Humans Liver Liver cells Liver, Artificial Methadone - pharmacology Morphine - pharmacology Narcotics Opiate Alkaloids - pharmacology Original Articles Physiological aspects Prototypes Tissue engineering
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