Normal birth after microsurgical enucleation of tripronuclear human zygotes: Case report

Microsurgical enucleation of a single pronucleus from each of three tripronuclear zygotes was performed and the embryos were transferred to a 38‐year‐old woman on day 3 after fertilization. A normal healthy baby boy was born at 38 weeks and 4 days gestation, demonstrating that with polyspermic ferti...

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Veröffentlicht in:Human reproduction (Oxford) 2003-06, Vol.18 (6), p.1319-1322
Hauptverfasser: Kattera, Suresh, Chen, Christopher
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creator Kattera, Suresh
Chen, Christopher
description Microsurgical enucleation of a single pronucleus from each of three tripronuclear zygotes was performed and the embryos were transferred to a 38‐year‐old woman on day 3 after fertilization. A normal healthy baby boy was born at 38 weeks and 4 days gestation, demonstrating that with polyspermic fertilization, removal of the extra male pronucleus allows the zygote to develop normally.
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source MEDLINE; Oxford Academic Journals (OUP); EZB Electronic Journals Library
subjects Adult
Biological and medical sciences
Cell Nucleus
Embryo Transfer
Female
Fertilization in Vitro
Fundamental and applied biological sciences. Psychology
Humans
Key words: embryos/enucleation/male pronuclei/oocytes/tripronuclear zygotes
Male
Microsurgery
Mother. Fetoplacental unit. Mammary gland. Milk
Oocyte Donation
Pregnancy
Pregnancy Outcome
Pregnancy. Parturition. Lactation
Vertebrates: reproduction
Zygote - ultrastructure
title Normal birth after microsurgical enucleation of tripronuclear human zygotes: Case report
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