Lactobacilli inhibit Shigella dysenteriae 1 induced pro-inflammatory response and cytotoxicity in host cells via impediment of Shigella –host interactions

Abstract Objective Shigella dysenteriae Type 1 dysentery is a major cause of morbidity and mortality in children from less developed and developing countries. The present study explores the hypothesis that lactobacilli protect the host cell during S. dysenteriae Type 1 infection and its mechanism of...

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Veröffentlicht in:	Digestive and liver disease 2010-01, Vol.42 (1), p.33-39
Hauptverfasser:	Moorthy, G, Murali, M.R, Niranjali Devaraj, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherence Bacterial Adhesion Caco-2 Cells Coculture Techniques Dysentery, Bacillary - immunology Dysentery, Bacillary - microbiology Gastroenterology and Hepatology Host-Pathogen Interactions - physiology HSP-70 HSP70 Heat-Shock Proteins - metabolism Humans Immunity, Innate Interleukin-8 - metabolism Internalization Lactobacilli Lactobacillus acidophilus - physiology Lactobacillus rhamnosus - physiology Shigella dysenteriae - immunology Shigella dysenteriae - physiology Shigella dysenteriae 1 Tumor Necrosis Factor-alpha - metabolism
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