Dose-ranging efficacy of sitagliptin, a dipeptidyl peptidase-4 inhibitor, in Japanese patients with type 2 diabetes mellitus

Sitagliptin is an oral, potent, highly selective, once-daily DPP-4 inhibitor indicated for the treatment of type 2 diabetes mellitus (T2DM). To assess the dose-ranging efficacy and safety/tolerability profile of once-daily sitagliptin 25, 50, 100, and 200 mg in Japanese patients with T2DM. In this r...

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Veröffentlicht in:	Endocrine Journal 2010, Vol.57(5), pp.383-394
Hauptverfasser:	Iwamoto, Yasuhiko, Taniguchi, Tadaaki, Nonaka, Kenji, Okamoto, Taro, Okuyama, Kotoba, Ferreira, Juan Camilo Arjona, Amatruda, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Area Under Curve Asian Continental Ancestry Group Diabetes Mellitus, Type 2 - drug therapy Dipeptidyl-Peptidase IV Inhibitors - administration & dosage Dose-Response Relationship, Drug Double-Blind Method DPP-4 inhibitor Female Glycemic control Humans Hypoglycemic Agents - administration & dosage Incretins Male Middle Aged MK-0431 Placebos Pyrazines - administration & dosage Sitagliptin Phosphate Treatment Outcome Triazoles - administration & dosage Young Adult
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