Effect of pioglitazone on various parameters of insulin resistance including lipoprotein subclass according to particle size by a gel-permeation high-performance liquid chromatography in newly diagnosed patients with type 2 diabetes

Pioglitazone is an insulin-sensitizing agent that has been reported to have anti-arteriosclerotic effects. The aim of this study was to obtain a better understanding of the mechanism involved in the insulin sensitizing effect of pioglitazone. A total of 50 newly diagnosed patients with type 2 diabet...

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Veröffentlicht in:	Endocrine Journal 2010, Vol.57(5), pp.423-430
Hauptverfasser:	Nakano, Koji, Hasegawa, Goji, Fukui, Michiaki, Yamasaki, Masahiro, Ishihara, Kiyoshi, Takashima, Tooru, Kitagawa, Yoshihiro, Fujinami, Aya, Ohta, Mitsuhiro, Hara, Hirokazu, Adachi, Tetsuo, Ogata, Masakazu, Obayashi, Hiroshi, Nakamura, Naoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Age of Onset Body Fat Distribution Chromatography, Gel - methods Chromatography, High Pressure Liquid - methods Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - epidemiology Female Hepatic insulin resistance Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - pharmacology Hypolipidemic Agents - administration & dosage Hypolipidemic Agents - pharmacology Insulin Resistance Large VLDL Lipoprotein subclass particle size Lipoproteins - analysis Lipoproteins - blood Lipoproteins - classification Male Metformin - administration & dosage Metformin - pharmacology Middle Aged Particle Size Pioglitazone Thiazolidinediones - administration & dosage Thiazolidinediones - pharmacology Time Factors
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