Iron/ethylcellulose (core/shell) nanoplatform loaded with 5-fluorouracil for cancer targeting

Even though 5-fluorouracil has been demonstrated to display antitumor activity against a wide variety of cancers, high doses are needed to bring out the required therapeutic activity that could simultaneously lead to severe side effects. We hypothesized that the efficient delivery of 5-fluorouracil...

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Bibliographische Detailangaben
Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2010-05, Vol.77 (1), p.111-116
Hauptverfasser:	Arias, José L., López-Viota, Margarita, Delgado, Ángel V., Ruiz, Mª Adolfina
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Antimetabolites, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - chemistry Antimetabolites, Antineoplastic - therapeutic use Biocompatible Materials Cellulose - analogs & derivatives Cellulose - chemistry Drug Delivery Systems Drug targeting Ethylcellulose Fluorouracil - administration & dosage Fluorouracil - chemistry Fluorouracil - therapeutic use Iron Iron - chemistry Magnetic core/shell colloidal particles Nanostructures Neoplasms - drug therapy Stimuli-sensitive drug carriers
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