The Effects of Simulated Airway Diseases and Affected Flow Distributions on Aerosol Deposition

Experimental and theoretical aspects of targeted drug delivery have been addressed several times in this journal. Herein, a computational study of particle deposition patterns within healthy and diseased lungs has been performed, using a validated aerosol dosimetry model and a flow-resistance model....

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Veröffentlicht in:	Respiratory care 2010-06, Vol.55 (6), p.707-718
Hauptverfasser:	APIOU-SBIRLEA, Gabriela, KATZ, Ira M, MARTONEN, Ted B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosol therapy Aerosols - therapeutic use Analysis Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Computer Simulation Dosage and administration Drug delivery systems Drug targeting Drug therapy Drugs Emergency and intensive respiratory care Humans Intensive care medicine Lung Diseases - drug therapy Lung Diseases - physiopathology Management Medical sciences Methods Models, Biological Patient outcomes Pulmonary Ventilation - physiology Respiratory agents Respiratory tract diseases Rheology Vehicles
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