Use of oral midazolam in pediatric upper gastrointestinal endoscopy
Background: The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy. Methods: Sixty‐one children (age
Gespeichert in:
| Veröffentlicht in: | Pediatrics international 2010-04, Vol.52 (2), p.191-195 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 195 |
|---|---|
| container_issue | 2 |
| container_start_page | 191 |
| container_title | Pediatrics international |
| container_volume | 52 |
| creator | Rafeey, Mandana Ghojazadeh, Morteza Feizo Allah Zadeh, Hosain Majidi, Hamideh |
| description | Background: The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy.
Methods: Sixty‐one children (age |
| doi_str_mv | 10.1111/j.1442-200X.2009.02936.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733105416</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733105416</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4866-20cab27ec7131a9d7df92762fb97b9d0b93bda46fde82a5243a60e2311491cb83</originalsourceid><addsrcrecordid>eNqNkEtP3DAUha2Kqjzav4AiNqwS_Bo_Fl2ggQLqqExVEN1ZTuwgT5M42Ik6w6-v0xmBxAovrq_k7xwdHwAyBAuUztmqQJTiHEP4u0hDFhBLwor1B3Dw8rCXdoJFLiDj--AwxhWEUHBBP4F9JBmjEMEDML-PNvN15oNustYZ_ewb3Wauy3prnB6Cq7Kx723IHnUcgnfdYOPgukTbzvhY-X7zGXysdRPtl919BO6_Xd7Nr_PF7dXN_HyRV1QwlkJVusTcVhwRpKXhppaYM1yXkpfSwFKS0mjKamMF1jNMiWbQYoIQlagqBTkCp1vfPvinMcVQrYuVbRrdWT9GxQlBcEYRS-TJG3Llx5BCR4URnqXviwkSW6gKPsZga9UH1-qwUQiqqWa1UlObampzGlL9r1mtk_R45z-WrTWvwl2vCfi6Bf66xm7ebayWlxfTlvT5Vu_iYNcveh3-KMYJn6mHH1cKku_XPy_wL7Uk_wCCmJoy</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>212519686</pqid></control><display><type>article</type><title>Use of oral midazolam in pediatric upper gastrointestinal endoscopy</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Rafeey, Mandana ; Ghojazadeh, Morteza ; Feizo Allah Zadeh, Hosain ; Majidi, Hamideh</creator><creatorcontrib>Rafeey, Mandana ; Ghojazadeh, Morteza ; Feizo Allah Zadeh, Hosain ; Majidi, Hamideh</creatorcontrib><description>Background: The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy.
Methods: Sixty‐one children (age <16 years) scheduled for upper GI endoscopy were studied. Patients were randomly assigned to receive oral or i.v. midazolam. Measurements were made and compared for vital signs, level of sedation, pre‐ and post‐procedure comfort, anxiety during endoscopy, ease of separation from parents, ease and duration of procedure, and recovery time.
Results: Patients were aged 1–16 years (mean 7.5 ± 3.42 years); 30 patients received oral medication, and 31 received i.v. medication. There were no statistically significant differences in age or gender between groups. There were no significant differences in level of sedation, ease of separation from parents, ease of ability to monitor the patient during the procedure, heart rate, systolic arterial pressure, or respiratory rate. Oxygen saturation was significantly lower in the i.v. group than the oral group 10 and 30 min after removal of the endoscope, and recovery time was longer in the oral than the i.v. group.
Conclusions: Oral administration of midazolam is a safe and effective method of sedation that significantly reduces anxiety and improves overall tolerance for children undergoing esophagogastroduodenoscopy.</description><identifier>ISSN: 1328-8067</identifier><identifier>EISSN: 1442-200X</identifier><identifier>DOI: 10.1111/j.1442-200X.2009.02936.x</identifier><identifier>PMID: 19664010</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Publishing Asia</publisher><subject>Administration, Oral ; Adolescent ; Anesthesia ; Child ; Child, Preschool ; children ; Drug delivery systems ; endoscopy ; Endoscopy, Gastrointestinal ; Esophagus ; Female ; Humans ; Hypnotics and Sedatives - administration & dosage ; Infant ; Injections, Intravenous ; Male ; Medical procedures ; midazolam ; Midazolam - administration & dosage ; oral ; Pediatrics ; Prospective Studies ; sedation ; Single-Blind Method</subject><ispartof>Pediatrics international, 2010-04, Vol.52 (2), p.191-195</ispartof><rights>2010 Japan Pediatric Society</rights><rights>Journal compilation © 2010 Japan Pediatric Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4866-20cab27ec7131a9d7df92762fb97b9d0b93bda46fde82a5243a60e2311491cb83</citedby><cites>FETCH-LOGICAL-c4866-20cab27ec7131a9d7df92762fb97b9d0b93bda46fde82a5243a60e2311491cb83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1442-200X.2009.02936.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1442-200X.2009.02936.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19664010$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rafeey, Mandana</creatorcontrib><creatorcontrib>Ghojazadeh, Morteza</creatorcontrib><creatorcontrib>Feizo Allah Zadeh, Hosain</creatorcontrib><creatorcontrib>Majidi, Hamideh</creatorcontrib><title>Use of oral midazolam in pediatric upper gastrointestinal endoscopy</title><title>Pediatrics international</title><addtitle>Pediatr Int</addtitle><description>Background: The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy.
Methods: Sixty‐one children (age <16 years) scheduled for upper GI endoscopy were studied. Patients were randomly assigned to receive oral or i.v. midazolam. Measurements were made and compared for vital signs, level of sedation, pre‐ and post‐procedure comfort, anxiety during endoscopy, ease of separation from parents, ease and duration of procedure, and recovery time.
Results: Patients were aged 1–16 years (mean 7.5 ± 3.42 years); 30 patients received oral medication, and 31 received i.v. medication. There were no statistically significant differences in age or gender between groups. There were no significant differences in level of sedation, ease of separation from parents, ease of ability to monitor the patient during the procedure, heart rate, systolic arterial pressure, or respiratory rate. Oxygen saturation was significantly lower in the i.v. group than the oral group 10 and 30 min after removal of the endoscope, and recovery time was longer in the oral than the i.v. group.
Conclusions: Oral administration of midazolam is a safe and effective method of sedation that significantly reduces anxiety and improves overall tolerance for children undergoing esophagogastroduodenoscopy.</description><subject>Administration, Oral</subject><subject>Adolescent</subject><subject>Anesthesia</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>children</subject><subject>Drug delivery systems</subject><subject>endoscopy</subject><subject>Endoscopy, Gastrointestinal</subject><subject>Esophagus</subject><subject>Female</subject><subject>Humans</subject><subject>Hypnotics and Sedatives - administration & dosage</subject><subject>Infant</subject><subject>Injections, Intravenous</subject><subject>Male</subject><subject>Medical procedures</subject><subject>midazolam</subject><subject>Midazolam - administration & dosage</subject><subject>oral</subject><subject>Pediatrics</subject><subject>Prospective Studies</subject><subject>sedation</subject><subject>Single-Blind Method</subject><issn>1328-8067</issn><issn>1442-200X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtP3DAUha2Kqjzav4AiNqwS_Bo_Fl2ggQLqqExVEN1ZTuwgT5M42Ik6w6-v0xmBxAovrq_k7xwdHwAyBAuUztmqQJTiHEP4u0hDFhBLwor1B3Dw8rCXdoJFLiDj--AwxhWEUHBBP4F9JBmjEMEDML-PNvN15oNustYZ_ewb3Wauy3prnB6Cq7Kx723IHnUcgnfdYOPgukTbzvhY-X7zGXysdRPtl919BO6_Xd7Nr_PF7dXN_HyRV1QwlkJVusTcVhwRpKXhppaYM1yXkpfSwFKS0mjKamMF1jNMiWbQYoIQlagqBTkCp1vfPvinMcVQrYuVbRrdWT9GxQlBcEYRS-TJG3Llx5BCR4URnqXviwkSW6gKPsZga9UH1-qwUQiqqWa1UlObampzGlL9r1mtk_R45z-WrTWvwl2vCfi6Bf66xm7ebayWlxfTlvT5Vu_iYNcveh3-KMYJn6mHH1cKku_XPy_wL7Uk_wCCmJoy</recordid><startdate>201004</startdate><enddate>201004</enddate><creator>Rafeey, Mandana</creator><creator>Ghojazadeh, Morteza</creator><creator>Feizo Allah Zadeh, Hosain</creator><creator>Majidi, Hamideh</creator><general>Blackwell Publishing Asia</general><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201004</creationdate><title>Use of oral midazolam in pediatric upper gastrointestinal endoscopy</title><author>Rafeey, Mandana ; Ghojazadeh, Morteza ; Feizo Allah Zadeh, Hosain ; Majidi, Hamideh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4866-20cab27ec7131a9d7df92762fb97b9d0b93bda46fde82a5243a60e2311491cb83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Administration, Oral</topic><topic>Adolescent</topic><topic>Anesthesia</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>children</topic><topic>Drug delivery systems</topic><topic>endoscopy</topic><topic>Endoscopy, Gastrointestinal</topic><topic>Esophagus</topic><topic>Female</topic><topic>Humans</topic><topic>Hypnotics and Sedatives - administration & dosage</topic><topic>Infant</topic><topic>Injections, Intravenous</topic><topic>Male</topic><topic>Medical procedures</topic><topic>midazolam</topic><topic>Midazolam - administration & dosage</topic><topic>oral</topic><topic>Pediatrics</topic><topic>Prospective Studies</topic><topic>sedation</topic><topic>Single-Blind Method</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rafeey, Mandana</creatorcontrib><creatorcontrib>Ghojazadeh, Morteza</creatorcontrib><creatorcontrib>Feizo Allah Zadeh, Hosain</creatorcontrib><creatorcontrib>Majidi, Hamideh</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatrics international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rafeey, Mandana</au><au>Ghojazadeh, Morteza</au><au>Feizo Allah Zadeh, Hosain</au><au>Majidi, Hamideh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of oral midazolam in pediatric upper gastrointestinal endoscopy</atitle><jtitle>Pediatrics international</jtitle><addtitle>Pediatr Int</addtitle><date>2010-04</date><risdate>2010</risdate><volume>52</volume><issue>2</issue><spage>191</spage><epage>195</epage><pages>191-195</pages><issn>1328-8067</issn><eissn>1442-200X</eissn><abstract>Background: The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy.
Methods: Sixty‐one children (age <16 years) scheduled for upper GI endoscopy were studied. Patients were randomly assigned to receive oral or i.v. midazolam. Measurements were made and compared for vital signs, level of sedation, pre‐ and post‐procedure comfort, anxiety during endoscopy, ease of separation from parents, ease and duration of procedure, and recovery time.
Results: Patients were aged 1–16 years (mean 7.5 ± 3.42 years); 30 patients received oral medication, and 31 received i.v. medication. There were no statistically significant differences in age or gender between groups. There were no significant differences in level of sedation, ease of separation from parents, ease of ability to monitor the patient during the procedure, heart rate, systolic arterial pressure, or respiratory rate. Oxygen saturation was significantly lower in the i.v. group than the oral group 10 and 30 min after removal of the endoscope, and recovery time was longer in the oral than the i.v. group.
Conclusions: Oral administration of midazolam is a safe and effective method of sedation that significantly reduces anxiety and improves overall tolerance for children undergoing esophagogastroduodenoscopy.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>19664010</pmid><doi>10.1111/j.1442-200X.2009.02936.x</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1328-8067 |
| ispartof | Pediatrics international, 2010-04, Vol.52 (2), p.191-195 |
| issn | 1328-8067 1442-200X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_733105416 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Administration, Oral Adolescent Anesthesia Child Child, Preschool children Drug delivery systems endoscopy Endoscopy, Gastrointestinal Esophagus Female Humans Hypnotics and Sedatives - administration & dosage Infant Injections, Intravenous Male Medical procedures midazolam Midazolam - administration & dosage oral Pediatrics Prospective Studies sedation Single-Blind Method |
| title | Use of oral midazolam in pediatric upper gastrointestinal endoscopy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T08%3A56%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Use%20of%20oral%20midazolam%20in%20pediatric%20upper%20gastrointestinal%20endoscopy&rft.jtitle=Pediatrics%20international&rft.au=Rafeey,%20Mandana&rft.date=2010-04&rft.volume=52&rft.issue=2&rft.spage=191&rft.epage=195&rft.pages=191-195&rft.issn=1328-8067&rft.eissn=1442-200X&rft_id=info:doi/10.1111/j.1442-200X.2009.02936.x&rft_dat=%3Cproquest_cross%3E733105416%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=212519686&rft_id=info:pmid/19664010&rfr_iscdi=true |