Nanomechanical Properties of Thin Films of Type I Collagen Fibrils

The mechanical cues that adherent cells derive from the extracellular matrix (ECM) can effect dramatic changes in cell migration, proliferation, differentiation, and apoptosis. Model ECMs composed of collagen fibrils formed from purified collagen are an important experimental system to study cell re...

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Veröffentlicht in:	Langmuir 2010-03, Vol.26 (5), p.3629-3636
Hauptverfasser:	Chung, Koo-Hyun, Bhadriraju, Kiran, Spurlin, Tighe A, Cook, Robert F, Plant, Anne L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomechanical Phenomena Chemistry Collagen Type I - chemistry Collagen Type I - metabolism Colloidal state and disperse state Elastic Modulus Exact sciences and technology Extracellular Matrix - metabolism General and physical chemistry Materials: Nano-and Mesostructured Materials, Polymers, Gels, Liquid Crystals, Composites Models, Biological Nanostructures Reproducibility of Results Surface physical chemistry
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