High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts

High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts

We previously described a fiber based Doppler optical coherence tomography system [1] capable of imaging embryo cardiac blood flow at 4~16 frames per second with wide velocity dynamic range [2]. Coupling this system to a linear scanning fiber optical catheter design that minimizes friction and vibra...

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Veröffentlicht in:Optics express 2003-09, Vol.11 (19), p.2416-2424
Hauptverfasser: Yang, Victor X D, Gordon, Maggie, Tang, Shou-Jiang, Marcon, Norman, Gardiner, Geoffrey, Qi, Bing, Bisland, Stuart, Seng-Yue, Emily, Lo, Stewart, Pekar, Julius, Wilson, Brian, Vitkin, I
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container_end_page 2424
container_issue 19
container_start_page 2416
container_title Optics express
container_volume 11
creator Yang, Victor X D
Gordon, Maggie
Tang, Shou-Jiang
Marcon, Norman
Gardiner, Geoffrey
Qi, Bing
Bisland, Stuart
Seng-Yue, Emily
Lo, Stewart
Pekar, Julius
Wilson, Brian
Vitkin, I
description We previously described a fiber based Doppler optical coherence tomography system [1] capable of imaging embryo cardiac blood flow at 4~16 frames per second with wide velocity dynamic range [2]. Coupling this system to a linear scanning fiber optical catheter design that minimizes friction and vibrations, we report here the initial results of in vivo endoscopic Doppler optical coherence tomography (EDOCT) imaging in normal rat and human esophagus. Microvascular flow in blood vessels less than 100 microm diameter was detected using a combination of color-Doppler and velocity variance imaging modes, during clinical endoscopy using a mobile EDOCT system.
doi_str_mv 10.1364/oe.11.002416
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title High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts
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