Performance of recalibrated ReFacto® laboratory standard in the measurement of FVIII plasma concentration via the chromogenic and one-stage assays after infusion of recalibrated ReFacto® (B-domain deleted recombinant factor VIII)

The use of ReFacto Laboratory Standard (RLS) in the one‐stage clotting assay was proposed to reduce the underestimation of factor VIII (FVIII) plasma concentration after the infusion of ‘ReFacto®’ (B‐domain deleted recombinant FVIII) in haemophilia A patients. Both ReFacto® and RLS were recently rec...

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Veröffentlicht in:	Haemophilia : the official journal of the World Federation of Hemophilia 2009-05, Vol.15 (3), p.779-787
Hauptverfasser:	SANTORO, C., IORIO, A., FERRANTE, F., PALLOTTA, A., PIGNOLONI, P., BIONDO, F., AGNELLI, G., MAZZUCCONI, M. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent B domain deleted recombinant FVIII Biological Assay Blood Coagulation Factor Inhibitors - analysis Blood Coagulation Factor Inhibitors - pharmacokinetics Blood Coagulation Tests - standards Child Chromogenic Compounds Clinical Laboratory Techniques - standards Factor VIII - analysis Factor VIII - pharmacokinetics haemophilia Hemophilia A - blood Hemophilia A - drug therapy Humans Infusions, Intravenous Male Peptide Fragments - blood Peptide Fragments - pharmacokinetics pharmacokinetics ReFacto Reference Standards Reproducibility of Results
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